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Literature review for - Flourish Paediatrics

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Table 26.2 Summary of studies used to make evidence statements <strong>for</strong> selenium and breastfeeding outcomes<br />

STUDY DETAILS<br />

(Review)<br />

Affiliation/source of<br />

funds<br />

Study design<br />

Level of evidence<br />

Date of search<br />

Number of studies<br />

Total number of<br />

participants<br />

Population<br />

characteristics<br />

Range of exposure<br />

Length of follow-up<br />

Outcome(s)<br />

measured<br />

INTERNAL<br />

VALIDITY<br />

Databases included<br />

in search<br />

Statistical analysis<br />

methods<br />

Overall quality<br />

assessment<br />

(Positive/Negative<br />

or Neutral) plus<br />

descriptive)<br />

RESULTS<br />

Dorea 2002<br />

University of Brazil<br />

Systematic <strong>review</strong><br />

III-2 Evidence obtained from comparative studies (including systematic <strong>review</strong>s of such studies) with concurrent controls and<br />

allocation not randomised, cohort studies, case-control studies, or interrupted time series with a control group.<br />

NS<br />

not reported but > 190 references<br />

NS<br />

NS; Lactating women from > 10 countries (developed and developing)<br />

Not relevant but a Table of Se concentrations in breastmilk given from 16 studies by stage of lactation. Table also given <strong>for</strong><br />

Se concentration <strong>for</strong> <strong>for</strong>e- and hind-milk.<br />

Selenium concentration in breast milk including <strong>for</strong>e and hind milk<br />

Medline and Web of Science<br />

O<br />

536

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