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Literature review for - Flourish Paediatrics

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hours.<br />

The GE rate was determined using a<br />

breath test<br />

The infants were randomly assigned a<br />

different sequence of possible postural<br />

combinations<br />

Impedance tracing was analysed <strong>for</strong><br />

liquid, gas, and mixed reflux findings<br />

using established criteria.<br />

Manometry tracings were analysed<br />

<strong>for</strong> transient lower esophageal<br />

sphincter relaxation (TLESRs).<br />

Quality 0 P P<br />

Results<br />

There was more TLESRs and GER<br />

episodes in the RLP (median<br />

TLESRs= 9.5, median GER= 11.5<br />

episodes/hour) compared to the LLP<br />

(median TLSERs = 5.5, median<br />

GER= 7.0 episodes/hour)<br />

The mean esophageal exposure to acid and<br />

non-acid GER was lower in the prone<br />

position (4.4% and 0.3% respectively) and<br />

left side (7.5% and 0.7% respectively) than<br />

in positions right side (21.4% and 1.2%<br />

respectively) and supine (17.6% and 1.3%)<br />

Recommendations were made on<br />

epidemiology, natural history,<br />

diagnosis and treatment of<br />

eosinophillic esophagitis.<br />

Effect on risk<br />

Clinical<br />

importance<br />

Clinical<br />

relevance<br />

Gastric half emptying time was<br />

significantly faster in the RLP first<br />

protocol compared with the LLP first<br />

protocol (37.0 ± 21.1 vs 61.2 ± 24.8)<br />

A strategy of RLP <strong>for</strong> the first<br />

postprandial hour with a positional<br />

change to the left thereafter may be<br />

effective in reducing liquid GER in<br />

the late postprandial period<br />

The study indicates placing premature<br />

infants in a prone or left lateral position<br />

during the postprandial period may limit<br />

GOR.<br />

4 4 1<br />

1 1 1<br />

261

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