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Literature review for - Flourish Paediatrics

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years in Wright 2001, while<br />

it ranged from 2 to 9 years<br />

in the other studies<br />

Meta-Analysis of<br />

prospective cohort studies<br />

of the association between<br />

asthma risk and<br />

breastfeeding ≥ 3 months<br />

<strong>for</strong> children without family<br />

history of asthma or atopy<br />

OR = 0.74 (0.60, 0.92)<br />

Effect on risk Decrease None Decrease Decrease<br />

Clinical 1 1 1 1<br />

importance<br />

Clinical 1 1 1 1<br />

relevance<br />

Generalisability N (Japan) Y Y Y<br />

Applicability Y Y Y Y<br />

Reference Ip 2007 Gdalevich 2001 Miyake 2008 Pediatr Allergy Immunol: Kusunoki 2010 Pediatr Allergy<br />

Immunol:<br />

Type of study Meta analysis Cohort study large-scale cross-sectional study<br />

Level of I (aetiology) II (aetiology) III (aetiology)<br />

evidence<br />

Definition of<br />

breastfeeding<br />

Exclusive breastfeeding duration was<br />

defined as the<br />

period when the infants were given only<br />

breast milk, (no <strong>for</strong>mula or solids) Water<br />

was not stated<br />

Complete breastfeeding.<br />

Mixed feeding.<br />

Complete artificial feeding.<br />

Asthma was categorised using a<br />

questionnaire comparable with the one<br />

401

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