Literature review for - Flourish Paediatrics

Table 24.4 Studies used to make evidence statements for breastfeeding and sudden infant death syndrome (SIDS)
STUDY DETAILS McVea, K.L.S., P.D. Turner, and D.K. Peppler 2000
(Review)
Reference
Affiliation/source of Olson centre for Women's Health, Nebraska
funds
Study design Meta analysis of 23 studies (18 case-controls, 4 nested case -controls, 1 cohort)
Level of evidence III-2 Evidence obtained from comparative studies (including systematic reviews of such studies) with concurrent controls
and allocation not randomised, cohort studies, case-control studies, or interrupted time series with a control group.
Date of search 1966-1997
Number of studies 23
Total number of >3100 cases
participants 50 000 controls
Population
Infant populations from UK, Australia, NZ, Canada, USA, ScandInavia.
characteristics
Range of exposure Included studies if a minimal definition of SIDs was met and original data was presented to allow calculation of an OR for
bottle feeding.
Length of follow-up Not applicable
Outcome(s) Inclusive definition of SIDS as any sudden, unexplained death of a young child.
measured
INTERNAL
VALIDITY
Databases included MEDLINE and additional hand searches of the references lists and key papers included in the meta-analysis
in search
Statistical analysis ORs and 95% CIs. Random effects model used in the meta-analysis due to heterogeneity of the studies with a pooled OR.
methods
Separate "pooled" OR for 2 groups of studies; those with "excellent" or "good" quality ratings published in last 10 years.
Overall quality P
assessment
(Positive/Negative
or Neutral) plus
descriptive)
527