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Literature review for - Flourish Paediatrics

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-0.49 to +0.41 episodes).Duncan 1993<br />

and Kramer2000a both found a slightly<br />

elevated risk <strong>for</strong> one or more episodes<br />

of otitis media pooled RR 1.28 (95% CI<br />

1.04 -1.57) (outcome56), but Duncan<br />

1993 found a nonsignificant reduction<br />

in risk <strong>for</strong> frequent otitis media RR 0.81<br />

(95% CI 0.43-1.52) (outcome57).<br />

EXTERNAL<br />

VALIDITY<br />

Generalisability y y - <strong>for</strong> the results of the studies<br />

conducted in developed countries<br />

Applicability y y y<br />

Comments The unclear randomization and<br />

allocation concealment processes in<br />

the study suggest selection bias was<br />

possible. Furthermore the use of a<br />

telephone interview further suggests<br />

recall/reporting bias<br />

Definitions of exclusive breastfeeding<br />

varied across studies<br />

Conclusion<br />

There remains considerable<br />

uncertainty about the effect of brief<br />

exposure to water, breast-milk<br />

substitutes, or other liquids on the<br />

success and duration of breastfeeding<br />

Infants who are exclusively breastfed<br />

<strong>for</strong> 6 mo experience less morbidity from<br />

gastrointestinal infection than those who<br />

are mixed breastfed as of 3 or 4 mo, and<br />

no deficits have been demonstrated in<br />

growth among infants from either<br />

developing or developed countries who<br />

are exclusively breastfed <strong>for</strong> 6 mo or<br />

longer. Moreover, the mothers of such<br />

infants have more prolonged lactational<br />

amenorrhea. Although infants should<br />

n<br />

In the cohort model of child mortality<br />

and stunting, the protective effect of<br />

breastfeeding is assumed to cease when<br />

the child reaches 2. Although authors<br />

have considered a number of<br />

breastfeeding interventions and <strong>review</strong>s,<br />

details of these interventions and<br />

<strong>review</strong>s are not provided.<br />

Proven nutrition-related interventions<br />

offer many possibilities <strong>for</strong> the<br />

reduction of the related burden of<br />

disease in both the short and the long<br />

term. The evidence <strong>for</strong> benefit from<br />

nutrition interventions is convincing.<br />

511

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