Literature review for - Flourish Paediatrics

Reference van Wijk et al. (2007) Corvaglia et al. (2007) Furuta et al. (2007)
Type of study Non- randomised cross over trial Non-randomised experimental trial SLR
Level of evidence III-2 (intervention) III-2 (intervention) I (aetiology)
Definition of
breastfeeding
Not defined Not defined Not defined
Intervention/
comparator
left lateral position (LLP) vs. right
lateral position (RLP)
supine position vs. prone position vs. on
the right side vs. on the left side
Esophageal exposure to acid and non acid
GOR
To develop consensus
recommendations on the diagnosis and
treatment of eosinophillic esophagitis
N 10 infants 22 754 infants and 323 adults
Population/study
information
Infants were healthy preterm infants
range premenstrual age (33-38
months) studied at a children’s
hospital in Adelaide.
Each infant was studied twice on 2
consecutive days and were subjected
to 2 positioning protocols in an RCT.
Infants were positioned in the left
lateral position (LLP) or the right
lateral position (RLP) and then
gavage-fed breastmilk or formula.
After one hour the position was
changed to the other side and
recording occurred for another 2
Premature infants with frequent
regurgitation and postprandial desaturation
were included in the study.
Reflux indexes were analysed with the
infants in 4 different positions; supine,
prone, on the right side and on the left side.
All infants were analysed for 24 hours.
Each infant received 8 meals and
underwent continues, simultaneous
measurement of intraesophageal pH and
multichannel electrical impedance.
Each subject measurement of GER was
recorded in different postural positions.
Reviewed English language medical
articles in 2006 relating to
eosinophillic esphagitis.
Most case reports