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Literature review for - Flourish Paediatrics

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gained 317.4 g more from birth to 1<br />

year<br />

0.17 kg, respectively; P = 0.17).<br />

Children who were breastfed <strong>for</strong> a<br />

longer duration and those who were<br />

breastfed without concurrent <strong>for</strong>mula<br />

feeding did not have significantly lower<br />

fat mass than did those children who<br />

were never breastfed.<br />

.<br />

Effect on risk Positive Positive Positive<br />

Clinical 1 1 1<br />

importance<br />

Clinical 1 1 1<br />

relevance<br />

Generalisability Y N N<br />

Applicability Y N N<br />

breastmilk gained weight more quickly<br />

than those receiving any breast milk.<br />

Conditional weight gain was also<br />

significantly associated with<br />

breastfeeding duration infants breastfed<br />

<strong>for</strong> less than 4 months gained weight<br />

more quickly than those breastfed <strong>for</strong><br />

longer, and this association remained<br />

after adjustment <strong>for</strong> age at introduction<br />

of solid foods. Both of these<br />

associations remained even after<br />

adjustment <strong>for</strong> the child’s height z-score<br />

at 3 years. (adjusted regression<br />

coefficient (difference<br />

in z-scores) 0.06, 95% CI 0.02 to 0.09),<br />

as did those<br />

breastfed <strong>for</strong> less than 4 months (0.05,<br />

95% CI 0.01 to<br />

0.09) versus those breastfed 4 months or<br />

longer.<br />

References used in body of evidence table: (Baker, Michaelsen et al. 2004; Burdette, Whitaker et al. 2006; Griffiths, Smeeth et al. 2009)<br />

435

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