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Literature review for - Flourish Paediatrics

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Intervention<br />

Comparator<br />

<strong>for</strong>mula was not classified<br />

as a complementary food.<br />

Introduction of comp foods<br />

16<br />

weeks<br />

N 5330 313<br />

Introduction of Comp foods<br />

be<strong>for</strong>e 4 months compared<br />

to >4 months<br />

(3) Age at introduction of<br />

solid foods: in which the<br />

mother introduced solids<br />

be<strong>for</strong>e four calendar months<br />

(17.4 weeks), ie, introduced<br />

solid foods early.<br />

Breastfeeding duration<br />

Population/study<br />

in<strong>for</strong>mation<br />

Danish National Birth<br />

Cohort<br />

(DNBC), a national cohort<br />

study<br />

313 preschool-aged children<br />

who were participating in a<br />

prospective cohort study<br />

(exposure data obtained<br />

retrospectively.<br />

Body composition measured<br />

using DEXA<br />

10 533 3-year-old children<br />

from the UK<br />

Millennium Cohort Study.<br />

Quality P N P P<br />

Results<br />

After adjustment the early<br />

introduction of comp foods<br />

resulted in 0.7kg heavier<br />

infant at 12 months<br />

Children did not differ<br />

significantly in fat mass if<br />

they were introduced to<br />

complementary foods be<strong>for</strong>e<br />

or after 4 mo of age (x ± SE<br />

4.49 ± 0.12 and 4.63 ± 0.12<br />

kg, respectively; P ± 0.42).<br />

Neither breastfeeding nor<br />

the timing of the<br />

introduction of<br />

complementary foods was<br />

associated with adiposity at<br />

age 5 y.<br />

Early introduction of solids<br />

was not associated with<br />

faster weight gain after<br />

adjustment <strong>for</strong> height z-<br />

score at 3 years (20.01, 95%<br />

CI 20.04 to 0.03).<br />

Included 22 SLR’s<br />

Quality 11 moderate and 11<br />

low.<br />

Factors associated with later<br />

overweight and obesity:<br />

maternal diabetes, maternal<br />

smoking, rapid infant<br />

growth, no or short<br />

breastfeeding, obesity in<br />

infancy, short sleep<br />

duration,

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