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Coronary Artery & Vessel Wall Imaging Hall B Monday 14:00-16:00 Computer 35 14:00 3664. Retrospective Estimation of 3D Respiratory Motion Vectors in Coronary MRI Alan Christopher O'Connor 1 , Mehdi Hedjazi Moghari 1 , Peng Hu 1 , Dana C. Peters 1 , Warren J. Manning 1 , Reza Nezafat 1 , Roger Ware Brockett 2 1 Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States; 2 SEAS, Harvard University, Cambridge, MA, United States Navigator correction methods were developed to increase the gating window size possible for free-breathing cardiac MRI and consequently reduce scan time. These methods typically rely on a generic scale-factor between measured diaphragm motion and heart motion. We present a novel scheme for estimating patient-, direction-, and coil-specific motion vectors directly from the scan data to correct for phase errors caused by respiratory motion of the heart. 14:30 3665. Quantitative Assessment of Right Coronary Artery MRI Using Quadrature RF Coils at 7 Tesla, Incorporating a Direct Comparison of Results to Those Acquired at 3 Tesla. Saskia van Elderen 1 , Maarten Versluis 1 , Jos Westenberg 1 , Harsh Agarwal 2 , Nadine Smith 1 , Matthias Stuber 3 , Albert de Roos 1 , Andrew Webb 1 1 Radiology, Leiden University Medical Center, Leiden, Netherlands; 2 Johns Hopkins University; 3 Department of Radiology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland Using a quadrature RF coil with dimensions optimized for reliable navigator gating, this study with ten volunteers shows that 7T right coronary angiograms can be acquired with improved vessel sharpness compared to those obtained at 3T using identical imaging parameters. 15:00 3666. The Influence of Sublingual Nitroglycerin on Contrast -Enhanced Whole-Heart Coronary Magnetic Resonance Angiography at 3.0-T Bin Sun 1 , ZhiYong Chen 2 , LiXin Jin 3 , Qing Duan 1 Radiology, FuJian Medical University Union Hospital, FuZhou, FuJian, China; 2 Radiology, FuJian Medical University Union Hospital, China; 3 Siemens Healthcare, MR Collaboration NE Asia, China This article describes the influence of sublingual nitroglycerin spray on the lumen diameter, number of side branches visualized, average vessel length of 3.0-T contrast-enhanced whole-heart coronary magnetic resonance angiography. Twenty-four patients were prospectively included in this study: 12 were examined without sublingual nitroglycerin, and 12 were examined after the administration of sublingual nitroglycerin. Two blinded observers quantitatively assessed lumen diameter and length in the RCA, LAD and LCX. The number of acute marginal branches and septal branches was counted. The number of clinical side effects was evaluated. Sublingual nitroglycerin spray significantly dilates the coronary arteries and allows more side branches to be visualized at 3.0-T contrast-enhanced whole-heart CMRA without increasing resolution or increasing the number of side effects. 15:30 3667. 3T Coronary MRA Using 3D Multi-Interleaved Multi-Echo Acquisition and VARPRO Fat-Water Separation Saurabh Shah 1 , Xiaoming Bi 1 , Diego Hernando 2 , Peter Weale 1 , Sven Zuehlsdorff 1 , Sonia Nielles-Vallespin 3 , Peter Kellman 4 1 Siemens Healthcare, Chicago, IL, United States; 2 University of Illinois at Urbana-Champaign, Urbana, IL, United States; 3 Royal Brompton And Harefield NHS Foundation Trust, London, United Kingdom; 4 National Institutes of Health / NHLBI, Bethesda, MD, United States A 3D free-breathing navigator-gated multi-interleaved multi-echo GRE sequence is implemented with VARPRO fat-water separation and utilized in targeted acquisition of coronary arteries at 3T. This approach achieves reliable fat-suppression across field-of-view and provides clear depiction of coronaries for enhanced visualization. Tuesday 13:30-15:30 Computer 35 13:30 3668. Prospective Respiratory Navigator Gated RF Excitation in Whole-Heart Coronary MRA at 3T Jing Yu 1,2 , Michael Schär, 23 , Harsh Agarwal, 2,4 , Matthias Stuber 2,5 1 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States; 2 Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States; 3 Philips Healthcare, Cleveland, OH, United States; 4 Department of Electrical and Computer Engineering, John Hopkins University, Baltimore, MD, United States; 5 Department of Radiology, University Hospital Center and University of Lausanne (CHUV), Lausanne, VD, Switzerland One of the challenges in coronary MRA is insufficient SNR. To improve the blood-pool SNR in prospective respiratory navigator gated whole-heart coronary MRA, radiofrequency excitations of the gradient echo readout train are suspended in real-time, when the respiratory position is outside the predefined gating window. Phase encoding is adapted to deposit the increased signal in central k- space and to minimize signal variation of adjacent k-space profiles. Consistent with the numerical simulation, in vivo experiments
demonstrated 35% improvement in blood-pool SNR, without compromising scan time or spatial resolution. The SNR advantage affords great potential towards better depiction of the coronary arteries. 14:00 3669. Coronary Sinus Flow Quantification at 3T and Cold Pressor Test for Non Invasive Evaluation of Coronary Endothelial Function Pierre-Julien Moro 1,2 , Alexis Jacquier 1 , Frank Kober 1 , Jean-Louis Bonnet 2 , Patrick Cozzone 1 , Monique Bernard 3 1 Centre de Résonance Magnétique Biologique et Médicale, CNRS UMR 6612, Université de la Méditerranée, Faculté de Médecine, Marseille, France; 2 Cardiology, CHU Timone, Marseille, France; 3 Centre de Résonance Magnétique Biologique et Médicale, CNRS UMR 6612, Université de la Méditerranée , Faculté de Médecine, Marseille, France The purpose of this study was to assess a non invasive measure of coronary endothelial function. Coronary sinus flow was measured in 14 volunteers at rest and during cold pressor test (CPT) using non breath-hold velocity encoded phase contrast cine MRI. Myocardial blood flow (MBF) significantly increased by 55 ± 38 % during CPT compared to the rest examination (p
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ELECTRONIC POSTER Cartilage Hall B
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14:00 3173. Sodium MRI: A Reproduci
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15:00 3182. Comparison of Short Ech
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15:00 3191. The Application of Magn
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to unity. Conversely, in trabecular
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determination of perfusion and perm
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unique ability of UTE MRI to direct
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throughout the maturation process,
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lipoatrophy with decreased of the l
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Tuesday 13:30-15:30 Computer 6 13:3
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14:30 3258. 3D-FSE-Cube of the Foot
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15:00 3267. Dynamic Hyperpolarized
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Hall B Monday 14:00-16:00 Computer
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hyperpolarized for use as a metabol
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15:30 3295. 1 H Decoupled 13 C MRS
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use of short and high bandwidth adi
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Wednesday 13:30-15:30 Computer 10 1
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14:30 3325. Modeling of 3-Dimension
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Thursday 13:30-15:30 Computer 11 13
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14:00 3345. An Optimized T1nom Appr
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Increasing spatial resolution is ad
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14:30 3362. NMR Plasma Profiling of
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Spectroscopic Localization & Imagin
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total scan time and remove the spac
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15:00 3394. Phase-Based Contrast Ag
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Tuesday 13:30-15:30 Computer 18 13:
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14:30 3922. Six Layers Stripline RF
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and a relaxed fixed point iteration
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15:00 3955. Improved PET Data Quant
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existing parallel imaging and parti
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Arterial Spin Labeling: Methods Hal
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using both methods but the differen
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Wednesday 13:30-15:30 Computer 62 1
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estimates. Differences in delays an
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angioplasty balloon in the aorta. T
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Cell Tracking II Hall B Monday 14:0
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are not sensitive to early abnormal
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were observed from the preCG and IC
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Vergata"; 6 Cognition and Cognitive
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secular-T2 peaks revealed significa
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Multiple Sclerosis I Hall B Monday
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independent predictors of disabilit
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Developing Brain I Hall B Monday 14
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suggests myelination or a reduction
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15:00 4392. Dti Study in the Infant
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improvements in motor deficit over
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DTI - Clinical Applications Hall B
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T2 and between lesion volume and AD
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significantly in rats exposed to EC
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Breast MR Hall B Monday 14:00-16:00
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therapies. MRI characteristics of t
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information is a novel approach. Th
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Metabolism Liver & Other II Hall B
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Wednesday 13:30-15:30 Computer 100
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Body Diffusion Hall B Monday 14:00-
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prevention. In this study we have e
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Tuesday 13:30-15:30 Computer 105 13
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present initial results in terms of
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14:30 4794. Bax-Deficiency Reduces
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of Cardiology, Munich University Ho
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appropriately describes the uptake
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tumour. A significant reduction in
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14:30 4838. Detection and Improveme
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15:00 4846. The Assessment of Early
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Our results indicate that the propo
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egularizing terms that may affect t
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times due to the need of additional
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proposed homotopic L0 minimization
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1 Imaging Division, UMC utrecht, Ut
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frequency k-space data are processe
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cylinders trajectory and have imple
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still requires scan durations not a
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14:00 5016. High Spatial and Tempor
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perform the AC of the SPECT data. T
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egularization parameter is adapted
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IDEAL knee MRI data is proposed. Va
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14:30 5129. Design of Iron Sensitiv
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