ELECTRONIC POSTER - ismrm

Thursday 13:30-15:30 Computer 93
13:30 4594. Flow Vector Analysis of Portal Venous Flow Using Time-SLIP (Time-Spatial
Labeling Inversion Pulse) with an Optical Flow Method
Akiyoshi Yamamoto 1 , Riichiro Nagashima 1 , Kentaro Haraoka 1 , Katsumi Nakamura 1 ,
Mitsue Miyazaki 2
1 Radiology, Tobata Kyoritsu Hospital, Kitakyushu, Fukuoka, Japan; 2 Toshiba Medical Research Institute, USA,
Vernon Hills, IL, United States
Flow vector analysis using optical flow can provide the useful information to assess portal venous hemodynamics enhancement using
Time-SLIP.
14:00 4595. In Vivo 1 H MRS of Gallbladder Bile Using an Optimized 8-Channel Phased Array
at 3T: Towards Improved Diagnosis of Hepatopancreatobiliary Diseases
Sanaz Mohajeri 1,2 , Tedros Bezabeh 1 , Scott B. King 1 , Omkar B. Ijare 1 , Gerald Y. Minuk 3 ,
Jeremy Lipschitz 4 , Ian C.P. Smith 1
1 National Research Council Institute for Biodiagnostics, Winnipeg, Manitoba, Canada; 2 Human Anatomy and
Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada; 3 Hepatology, University of Manitoba,
Winnipeg, Manitoba, Canada; 4 Surgery, University of Manitoba, Winnipeg, Manitoba, Canada
Considering the key role of liver in body metabolism, the study of bile composition is of great importance. In vitro 1 H MRS of bile
samples have shown diagnostic value in detecting various hepatopancreatobiliary disorders. Given the invasive nature of this
procedure, we considered the possibility of gathering in vivo data. We present here our initial efforts to obtain bile spectra from pigs
using a 3T clinical scanner comparing the use of a Siemens body array coil with an optimized home-built receive array coil.
14:30 4596. Inhibited Hepatobiliary Excretion Is a Sign of Cholangiocarcinoma in Patients with
Primary Sclerosing Cholangitis
Lena M. Hallberg 1 , Annika Bergquist 2 , Nils Albiin 1
1 Radiology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden; 2 Gastroenterology and
Hepatology, Karolinska University Hospital, Karolinska Insitutet, Stockholm, Sweden
Cholangiocarcinoma is a well known threat to patients with primary sclerosing cholangitis (PSC). Although, early diagnosis is crucial
for curative surgical treatment, it is difficult to differentiate malignant strictures from benign. We wanted to see if excretion
hepatobiliary contrast was inhibited in affected segments, as a sign of malignancy. Therefore, six patients with PSC and a
histopathologically confirmed cholangiocarcinoma , were examined in a 1.5 T MRI and Gd-BOPTA i.v. administered. In five of these
patients there was no sign of excretion in affected segments. Thus, inhibited hepatobiliary excretion is a sign of cholangiocarcinoma in
patients with primary sclerosing cholangitis.
15:00 4597. Gd-EOB-DTPA Enhanced MR Imaging: Evaluation of Enhancement Effects and
Enhancement Patterns in Hepatic Hemangioma
Tsutomu Tamada 1 , Atsushi Higaki 1 , Akihiko Kanki 1 , Satoko Okamoto 1 , Katsiyoshi Ito 1
1 Dept. of Radiology, Kawasaski Medical School, Kurashiki-city, Okayama, Japan
We assessed quantitatively and qualitatively the enhancement effects and the enhancement patterns of hepatic hemangioma and
normal liver tissue on Gd-EOB-DTPA-enhanced MR imaging. It will be important to know that the dynamic enhancement pattern of
hepatic hemangioma is similar to that of hepatocellular carcinoma, probably due to the washout of Gd-EOB-DTPA in the early stage
after contrast media administration compared with extracellular Gd chelates.
Lung MRI
Hall B Monday 14:00-16:00 Computer 94
14:00 4598. First Results from Clinical Sitings of a High Production Prototype Xenon Polarizer
F. William Hersman 1,2 , Jeff Ketel 2 , Iulian Constantin Ruset, 1,2 , Stephen Ketel 2 , Isabel
Dregely 1 , Walter Porter 2 , David W. Watt 2 , John P. Mugler, III 3 , Talissa A. Altes 3 , Kai
Ruppert 3 , Jaime F. Mata 3 , Samuel Patz 4 , Hiroto Hatabu 4 , Mirko Hrovat 5 , Iga Muradian 4 ,
Mikayel Dabaghyan 4 , G. Wilson Miller 3 , Chengbo Wang 3 , James P. Butler 6 , Jan H.
Distelbrink 2
1 University of New Hampshire, Durham, NH, United States; 2 Xemed LLC, Durham, NH, United States;
3 University of Virginia, Charlottesville, VA, United States; 4 Brigham and Women's Hospital, Boston, MA,
United States; 5 Mirtech, Inc, Brockton, MA, United States; 6 Harvard School of Public Health, Boston, MA,
United States
Hyperpolarized xenon-129 is potentially the most viable contrast agent to be used for characterizing pulmonary function by MRI.
Further improvements in polarizing technology yield production rates of up to 15 liters/hour with 50% polarization. This high
production prototype polarizer was relocated to two clinical sites and demonstrated in pilot clinical studies. First fully engineered
systems based on this design, XeBox-E10, will be available in 2010 for collaborative research.