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14:00 5068. Accelerated Point Spread Function Mapping Using Compressed Sensing for EPI<br />

Geometric Distortion Correction<br />

Iulius Dragonu 1 , Juergen Hennig 1 , Maxim Zaitsev 1<br />

1 Diagnostic Radiology, University Hospital Freiburg, Freiburg, Baden Wuerttemberg, Germany<br />

Single-shot echo-planar imaging (EPI) is a fast technique allowing the acquisition of an image following a single RF excitation. The<br />

high temporal resolution of EPI makes it the method of choice for applications such as fMRI or diffusion tensor imaging. However,<br />

EPI is prone to geometric and intensity distortions in the presence of magnetic field inhomogeneities. Several correction techniques<br />

have been proposed in the past based on field map acquisitions or point spread function (PSF) acquisitions. Parallel imaging<br />

techniques were employed for accelerating the PSF data acquisition. In this work we demonstrate that compressed sensing (CS)<br />

reconstruction can be used for acquiring the PSF data set with high acceleration factors for accurate geometric distortion corrections.<br />

14:30 5069. Distortion Correction for Echo Planar MR Imaging Using the Point Spread<br />

Function (PSF) Map with Bregman Iteration<br />

Yu Cai 1 , Weili Lin, Qingwei Liu, Craig Hamilton 2 , Hongyu An<br />

1 Department of Radiology, University of North Carolina-Chapel Hill, Chapel Hill, NC, United States; 2 Wake<br />

Forest University<br />

Point Spread Function (PSF) mapping techniques have shown promise for geometric distortion correction in Echo Planar Imaging<br />

(EPI)(1), where the distortion information is mapped by applying additional phase encoding gradients with a constant time (PSF<br />

encoding). Cai et al(2) introduced the inverse solution of the PSF map with the Tikhonov regularization method for EPI distortion<br />

correction. The smoothness penalty in the Tikhonov regularization causes it sensitive to the aliasing artifact in its reconstructed image<br />

and fine textile structure blurring. Here we apply the total variation (TV) regularization with Bregman iteration method(3) to the PSF<br />

map in which the penalty term is adaptively updated based on the Bregman distance, which is immune to the above effects. The<br />

proposed approach compared with the Tikhonov regularization methods were evaluated at 3.0T with human subjects while at 9.4T<br />

with rats.<br />

15:00 5070. Improved PSF-Based EPI Distortion Correction in Human Imaging at 7 Tesla<br />

Myung-Ho In 1 , Jun-Young Jung 2 , Se-Hong Oh 2 , Maxim Zaitsev 3 , Zang-Hee Cho 2 , Oliver<br />

Speck 1<br />

1 Department Biomedical Magnetic Resonance, Institute for Experimental Physics, Otto-von-Guericke<br />

University Magdeburg, Magdeburg, Germany; 2 Neuroscience Research Institute, Gachon University of<br />

Medicine and Science, Inchoen, Korea, Republic of; 3 Department of Radiologic Research, Medical Physics,<br />

University Hospital Freiburg, Freiburg, Germany<br />

This method proposes an improved method with which distortions in EPI images in the ultra high field MRI such as 7.0 Tesla can be<br />

correct automatically and with high fidelity. The correction is a modification and extension of the point spread function (PSF) method<br />

previously developed. In addition to more precise mapping and correction of blurring, the method removes flow induced artifacts<br />

which can cause errors in the shift map derived from the PSF. The advantages of the proposed method for the correction of geometric<br />

distortions in EPI are demonstrated in human brain in vivo at 7.0 Tesla.<br />

Topics in Image Analysis<br />

Hall B Monday 14:00-16:00 Computer 124<br />

14:00 5071. Automated Analysis of ACR Phantom Data as an Adjunct to a Regular MR Quality<br />

Assurance Program<br />

Lawrence P. Panych 1,2 , Lisa Bussolari 1 , Robert V. Mulkern, 23<br />

1 Radiology, Brigham and Women's Hospital, Boston, MA, United States; 2 Radiology, Harvard Medical School,<br />

Boston, MA, United States; 3 Radiology, Children's Hospital, Boston, MA, United States<br />

A Matlab-based package for automatic analysis of phantom images was developed. The package analyzes images of the American<br />

College of Radiology (ACR) phantom, performing measurements similar to those required as part of the ACR accreditation program<br />

along with other useful measures. Analysis of the data from five 1.5T MR systems acquired during weekly QA scans was performed.<br />

Such data can be help to identify potential system problems, such as lower than usual SNR, and serve as an adjunct to a regular<br />

program of quality assurance.<br />

14:30 5072. Weisskoff Stability Metrics Dependence on K-Space Trajectory<br />

E. Brian Welch 1,2 , Ad Moerland 3 , Elizabeth A. Moore 3 , J. Christopher Gatenby 1 , John C.<br />

Gore 1<br />

1 Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN,<br />

United States; 2 MR Clinical Science, Philips Healthcare, Highland Heights, OH, United States; 3 MR Clinical<br />

Science, Philips Healthcare, Best, Netherlands<br />

Measurement of an MR scanner’s signal stability is important for clinical and research sites acquiring data known to be adversely<br />

affected by system instabilities such as functional MRI. In particular, the Weisskoff plot and its associated radius of decorrelation<br />

(RDC) metric are often used to compare systems. The RDC is known to be influenced by the noise level of the data. However, it has<br />

not been widely reported that the observed RDC is also affected by k-space trajectory. Here we present stability measurements from a<br />

single scanner collected using four distinct k-space acquisition trajectories: Cartesian, multivane (propeller), spiral and radial.

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