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14:30 5053. Improvement of the Arterial Input Function Considering B 1 -Inhomogeneities<br />

Robert Merwa 1 , Karin Kapp 2 , Franz Ebner 3 , Thorsten Feiweier 4 , Gernot Reishofer 3 ,<br />

Rudolf Stollberger 5<br />

1 Medical Engineering, FH OÖ - Upper Austria University of Applied Sciences, Linz, Austria; 2 Department of<br />

Radiation Therapy, Medical University of Graz, Graz, Austria; 3 Department of Radiology, Medical University<br />

of Graz, Graz, Austria; 4 Healthcare, Siemens AG, Germany; 5 Institute of Medical Engineering, Graz University<br />

of Technology, Graz, Austria<br />

DCE MRI was performed at 3 T in combination with a special sequence in order to determine B 1 inhomogenities. AIF and tissue<br />

concentrations were calculated and the kinetic parameters K trans and V e were determined with a generalized kinetic model. The<br />

absolute deviation of the maximum value of two comparable AIFs can be improved by a factor up to 70 and the root mean square<br />

deviation concerning the two AIFs can be decreased by a factor up to 30 if B 1 inhomogeneities are corrected. Also the deviations of<br />

Ktrans and Ve in respect of the two AIFs are significantly lower.<br />

15:00 5054. Stent Imaging Using Metal Artifact Reduction Sequence<br />

Sang-Young Zho 1 , Min Oh Ghim 1 , Dong Joon Kim 2 , Dong-Hyun Kim 1,2<br />

1 Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of; 2 Radiology, Yonsei<br />

University College of Medicine, Seoul, Korea, Republic of<br />

We examine a method for high-resolution stent imaging using metal artifact correction sequence and parallel imaging technique.<br />

EPI Correction<br />

Hall B Monday 14:00-16:00 Computer 123<br />

14:00 5055. Robust Elimination of EPI Nyquist Ghosts Via Spatial and Temporal Encoding<br />

W Scott Hoge 1 , Huan Tan 2 , Robert A. Kraft 2<br />

1 Radiology, Brigham and Women's Hospital, Boston, MA, United States; 2 Virgina-Tech Wake Forest School of<br />

Biomedical Engineering, Winston-Salem, NC, United States<br />

Nyquist ghosts are an inherent artifact in EPI acquisitions. We propose here a method that fuses ghost correctuion methods based on<br />

spatial encoding (via multiple coils) and temporal encoding (via cyclic variations in the acquisition sequence). Post acquisition,<br />

PLACE is employed to cancel ghosting artifacts in data used to estimate self-referenced parallel MR imaging reconstruction<br />

coefficients. The improved pMRI reconstruction coefficients are then employed on each frame, to reconstruct a ghost free image. We<br />

demonstrate that this self-referenced approach significantly reduces Nyquist ghosts, and is robust to temporal variations such as<br />

magnetic field drift with minimal latency.<br />

14:30 5056. Optimized Acquisition Strategy for Reference-Free Reduction of Nyquist Ghosting<br />

in EPI at 7 T<br />

Benedikt A. Poser 1,2 , Pål Erik Goa, 1,3 , Markus Barth, 1,2<br />

1 Erwin L Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany;<br />

2 Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands;<br />

3 Department of Medical Imaging, St. Olavs University Hospital, Trondheim, Norway<br />

Nyquist (N/2) ghosting in EPI tends to become particularly problematic at ultra-high field. Strongly dependent on imaging parameters<br />

–especially echo spacing and readout bandwidth– ghosting may pose considerable practical limitations when setting up fMRI<br />

protocols at 7 T and above.<br />

We here show that residual ghosting is caused by an often appreciable mismatch between phase correction and imaging data. We<br />

propose a small but powerful sequence modification, namely an optimized timing of the phase-correction navigators, to overcome this<br />

problem and thereby remove the practical restrictions due to ghosting. Phantom and in vivo results demonstrate ghost reductions by up<br />

to factor four.<br />

15:00 5057. Robust Method for EPI Ghost Correction<br />

Frank Godenschweger 1 , Myung-Ho In 1 , Oliver Speck 1<br />

1 Biomedical Magnetic Resonance, Institute for Experimental Physics, Otto-von-Guericke University,<br />

Magdeburg, Germany<br />

A Nyquist ghost correction of EPI is propose, which determines the phase correction differences between channels and slices with<br />

high accuracy in a preparation step from a set of navigator echoes. Taking this calibration into account, only one single correction<br />

needs to be determined dynamically for all slices and channels during the EPI series, greatly improving stability.<br />

The robustness of the proposed technique was tested on phantom and in-vivo data. The proposed technique for EPI ghost correction<br />

dramatically improves the image quality.

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