ELECTRONIC POSTER - ismrm

14:30 3697. Time-Resolved Spin-Labeled Balanced SSFP Cineangiography for Visualizing
Intracardiac Shunt
Federico E. Mordini 1 , Ioannis Koktzoglou 1 , Robert R. Edelman 1
1 Radiology, NorthShore University HealthSystem, Evanston, IL, United States
Existing methods for intracardiac shunt evaluation have important technical limitations. We developed a time-resolved spin-labeled
cineangiographic technique (SLC) to image tagged blood within the heart for visualization of intracardiac shunt. Ten subjects with
known atrial septal defects (ASD) were evaluated. Tagged inflowing blood was depicted with high signal intensity (SI) while nontagged
blood was suppressed. Flow was visualized crossing the atrial septum both inplane and throughplane. In conclusion, SLC is a
non-contrast, non-velocity dependent method for visualizing RF-tagged blood flowing through cardiac chambers. SLC successfully
depicted intracardiac shunting in all patients. SLC has potential use in the detection and pre-procedural assessment of ASD.
15:00 3698. Evaluation of Diastolic Function with Flow Quantification Phase Contrast Cardiac
Magnetic Resonance Imaging
Jeremy Douglas Collins 1 , Philip Anthony Hodnett 1 , Timothy Anthony Scanlon 1 , Amir H.
Davarpanah 1 , Aya Kino 1 , Karin Dill 1 , Sven C. Zuehlsdorff 2 , James C. Carr 1
1 Radiology, Northwestern University, Chicago, IL, United States; 2 Radiology, Siemens Healthcare, MR
Research and Development, Chicago, IL, United States
Cardiac magnetic resonance is the reference standard for assessment of infiltrative heart disease and systolic function. The ability to
assess diastolic dysfunction would enable comprehensive assessment of cardiac function. We evaluated 36 patients and 4 volunteers
with flow quantification phase contrast imaging, comparing to Doppler echocardiography. Phase contrast imaging correctly classified
all patients with grade I diastolic dysfunction. Differentiating patients with grade II dysfunction from normal diastolic function was
not possible, although stratification based on E wave deceleration time was promising. A dedicated acquisition to assess the E’ lateral
annulus velocity may be useful in this regard.
15:30 3699. Highly Accelerated Cine Phase-Contrast Flow Measurements Using k-T PCA with
Spatial Compartments
Daniel Giese 1,2 , Verena Knobloch 1 , Henrik Pedersen 3 , Tobias Schaeffter 2 , Sebastian
Kozerke 1,2
1 Institute for Biomedical Engineering, Univeristy and ETH Zurich, Zurich, Switzerland; 2 Division of Imaging
Sciences, King's College London, London, United Kingdom; 3 Functional Imaging Unit, Glostrup Hospital,
Glostrup, Denmark
In this work, we present an extension of k-t PCA taking into account temporal correlations in spatial compartments. The compartment
method is shown to significantly outperform conventional k-t PCA at high reduction factors. Using the approach up to 10- fold net
acceleration of single-directional phase-contrast velocity mapping in the ascending and descending aorta is demonstrated with
excellent agreement relative to fully sampled data even if only a single receive coil is available.
Tuesday 13:30-15:30 Computer 37
13:30 3700. Carotid Artery Wall Shear Stress: Distribution, Correlation with Geometry and
Effect of Atherosclerosis
Michael Markl 1 , Timo Zech 2 , Simon Bauer 1 , Felix Wegent 2 , Aurelien F. Stalder 1 ,
Christoph Strecker 2 , Andreas Harloff 2
1 Diagnostic Radiology, Medical Physics, University Hospital, Freiburg, Germany; 2 Neurology, University
Hospital, Freiburg, Germany
The purpose of this study was to assess the physiological distribution of absolute wall shear stress and oscillatory shear index in the
entire carotid bifurcation in healthy volunteers (n=64 carotid bifurcations) and to evaluate their dependence on individual bifurcation
geometry. Further, the distribution of critical wall parameters was compared with findings in patients with moderate internal carotid
artery (ICA) stenosis before (n=6) and after surgical recanalization (n=11). Bifurcation geometry predicted exposure to critical wall
parameters and may thus be an indicator for the risk of developing flow-mediated atherosclerosis. Carotid artery stenosis and
treatment altered the distribution of critical wall parameters.