ELECTRONIC POSTER - ismrm

3 Department of Radiology, St Thomas' Hospital, London; 4 Department of Hepatology, Addenbrooke's Hospital,
Cambridge, Cambridgeshire, United Kingdom
Standard imaging techniques are insensitive to liver fibrosis. Current clinical assessment of liver fibrosis requires a biopsy, which risks
complications and sampling error. This work describes our experience with 2 new MR techniques: MR elastography and 31P
spectroscopy. MR elastography was found to correlate with histological grade of fibrosis in contrast to 31P PME/PDE ratio. Our
findings do not correlate with previous work. This may be because histological grade in our study was based on the original report,
rather than review of the biopsy material. We plan to repeat the analysis of our results with this data.
15:00 4661. Use of a Two-Point Dixon VIBE Sequence for Post-Contrast Liver MRI:
Comparison with Standard Chemically-Selective Fat-Suppressed VIBE for Image Quality
and Lesion Detection
Andrew B. Rosenkrantz 1 , Lorenzo Mannelli 1 , Sungheon Kim 1 , James Babb 1
1 Radiology, NYU Langone Medical Center, New York, NY, United States
In 30 consecutive patients at 1.5T, a breath-hold two-point Dixon VIBE acquisition was obtained of the liver immediately following a
standard chemically-selective fat-suppressed VIBE acquisition, both performed during the equilibrium phase after intravenous contrast
administration. Compared with the standard VIBE sequence, the Dixon VIBE sequence demonstrated significantly improved strength
of fat suppression, homogeneity of fat suppression, vessel sharpness, and subjective overall image quality. There were no significant
differences between the two sequences for sensitivity or PPV for focal liver lesion detection. We conclude that Dixon-VIBE achieved
higher image quality with preserved diagnostic ability for post-contrast liver MRI.
Bowel
Hall B Monday 14:00-16:00 Computer 98
14:00 4662. Fast 3D Tracking of 19F Labeled Small Capsules for Combined Morphology and
Real-Time Flow Studies in the Gastrointestinal Tract
Tobias Hahn 1 , Sebastian Kozerke 1 , Mark Fox 2,3 , Werner Schwizer 2 , Andreas Steingoetter,
1,4 , Michael Fried 2 , Peter Boesiger 1
1 Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Zurich, Switzerland; 2 Division of
Gastroenterology and Hepatology, University Hospital Zurich; 3 Nottingham Digestive Diseases Centre and
Biomedical Research Unit Queen's Medical Centre, University Hospital Nottingham; 4 Institute of Radiology,
Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
3D tracking of small-sized 19F labeled capsules is studied using fast modified balanced FFE sequences for concurrent measurements
of gastrointestinal function and morphology. Perfluoro-15-crown-5-ether and Hexafluorobenzene are proposed and studied for use as
tracking mediums. The proposed imaging protocol is shown to be reliable in tracking small capsules through realistic abdominal
phantoms and might therefore bear potential of being a valuable tool in detecting abnormal gastric function and at the same time
posing the basis for creating a 3D anatomical model of the complex bowel geometry.
14:30 4663. MR Fluoroscopy for Gastrointestinal Malrotation in Unsedated Infants
Owen John Arthurs 1 , Ilse Joubert 1 , Martin John Graves 1 , Pat Set 1 , David John Lomas 1
1 Department of Radiology, University of Cambridge and Addenbrooke's Hospital, Cambridge, Cambridgeshire,
United Kingdom
Gut malrotation is a congenital disorder of abnormal intestinal rotation, for which the current diagnostic technique is an upper GI X-
ray contrast study. This study evaluated the feasibility of interactive MR fluoroscopy for defining the gastro-intestinal tract anatomy in
un-sedated children with suspected malrotation. We imaged 9 children using both X-ray fluoroscopy, FIESTA and interactive SSFSE
MR imaging. We confidently identified the DJ flexure (7/9; 77%), orientation of the SMA / SMV (8/9; 88%) and the caecum (9/9;
100% using MRI. Interactive MR Fluoroscopy is feasible for gut imaging in un-sedated children.
15:00 4664. Customised Rotational Imaging Support for Paediatric MRI (CRISP-MRI)
Owen John Arthurs 1 , Erich Zammer 2 , David John Lomas 1
1 Department of Radiology, University of Cambridge and Addenbrooke's Hospital, Cambridge, Cambridgeshire,
United Kingdom; 2 Department of Orthopaedics, University of Cambridge and Addenbrooke's Hospital,
Cambridge, Cambridgeshire, United Kingdom
Traditional X-ray fluoroscopy methods for upper gastro-intestinal (GI) tract imaging in children require postural alteration to help
move contrast media to the required locations. In order to establish an equivalent MRI technique for imaging the paediatric gut, we
have developed a custom-built coil insert which allows for gentle rotation of a child within a rigid surface coil. It has a Vitrothene
polymer backing, with a Plastazote foam insert, which is currently for orthopaedic supports in our hospital. These materials are strong,
non-ferromagnetic, easily cleanable, lightweight and breathable. This type of device should help facilitate MR fluoroscopy in small
children.