ELECTRONIC POSTER - ismrm

14:00 3625. Rapid Quantification of Arterial Input Function and Myocardial T1 Changes in
Mice During Contrast Agent Injection
Wen Li 1,2 , Wei Li 1,2 , Chris Flask 2,3 , Mark Griswold 2,3 , Xin Yu 1,2
1 Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States;
2 Case Center for Imaging Research, Case Western Reserve University, Cleveland, OH, United States;
3 Department of Radiology, Case Western Reserve University, Cleveland, OH, United States
A modified ECG-triggered saturation recovery Look-Locker (MSRLL) method was developed for quantification of arterial input
function via rapid T1 mapping in dynamic contrast enhanced MRI (DCE-MRI) studies. High temporal resolution (< 2 min) was
achieved by acquiring only the low spatial frequency lines. High spatial frequency lines acquired before contrast were used to generate
composite images with higher spatial resolution. Validation was performed by comparing T1 values measured with SRLL and
MSRLL method in both phantom and in vivo mouse heart. The in vivo application of MSRLL in DCE-MRI studies was demonstrated
in mouse heart. These results suggest that MSRLL may provide a robust method for rapid T1 mapping of blood and myocardium in
cardiac DCE-MRI studies.
14:30 3626. The Contribution of Cardiac Motion to Dark Rim Artifacts in Myocardial Perfusion
Scans
Li Zhao 1 , Michael Salerno 2 , Christopher M. Kramer, 23 , Craig H. Meyer 1,3
1 Biomedical Enginnering, University of Virginia, Charlottesville, VA, United States; 2 Medicine, University of
Virginia, Charlottesville, VA, United States; 3 Radiology, University of Virginia, Charlottesville, VA, United
States
The Dark Rim artifacts in adenosine stress perfusion imaging are not completely understood, with Gibb’s ringing and cardiac motion
thought to be contributing factors. In this work we provide strong support to the idea that dark rim artifacts come from motion by
experimental data, and it also shows that these artifacts are more significant in some portions of the cardiac cycle than in others.
Moreover, a 1D motion model is developed and used to predict how dark rim artifacts vary over the cardiac cycle.
15:00 3627. A Comprehensive MR Examination of the Heart in Less Than 25 Minutes Using a
Semi-Automated Image Acquisition Prototype
Michaela Schmidt 1 , Giso von der Recke 2 , Peter Speier 3 , Saurabh Shah 4 , Carmel Hayes 3 ,
David Hardung 2 , Heyder Omran 5 , Edgar Mueller 6
1 MR Application Development, Healthcare Sector, Siemens AG , Erlangen, Germany; 2 St.-Marien-Hospital ,
Bonn, Germany; 3 MR Application Development, Healthcare Sector, Siemens AG, Erlangen, Germany; 4 MR
R&D, Healthcare Sector, Siemens AG, Chicago, IL, United States; 5 St.-Marien-Hospital, Bonn, Germany; 6 MR
Application Development, Healthcare Sector, Siemens AG, erlangen, Germany
In this study we evaluated a prototype designed for simplicity and speed in CMR examinations. Sixty five patients with suspected
ischemic heart disease were imaged with the prototype. The prototype offers, among others, user guidance and patient-centric
parameters, simplified, marker-based localization of the heart and automatic FOV calculation. Two users were experienced in and one
user was inexperienced in CMR imaging. Without reducing the accuracy and quality of the result, examination times below 25
minutes could be achieved for the experienced users, the beginner managed to successfully complete cardiac examinations with
excellent image quality in around 30 minutes.
Thursday 13:30-15:30 Computer 32
13:30 3628. High Resolution 3D Cardiac Perfusion Imaging Using Compartment-Based k-T
PCA
Viton Vitanis 1 , Robert Manka, 1,2 , Henrik Pedersen 3 , Peter Boesiger 1 , Sebastian Kozerke 1
1 Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland; 2 German Heart Institute Berlin, Berlin,
Germany; 3 Functional Imaging Unit, Glostrup Hospital, Glostrup, Denmark
k-t PCA is an extension of k-t SENSE aiming at improving reconstruction of non-periodic dynamic images. It is based on a
decomposition of the training and undersampled data into a temporally and a spatially invariant term using principal component
analysis. In this abstract, a compartment based k-t PCA reconstruction approach is presented, which aims at improving highly
undersampled, high-resolution 3D myocardial perfusion imaging by constraining the temporal content of different compartments in
the image series based on the bolus arrival times and prior knowledge about the perfusion curves.
14:00 3629. Highly Accelerated 3D SSFP First-Pass Myocardial Perfusion at 3T Using a 32-
Channel Coil
Matteo Milanesi 1 , Thomas K. Foo 2 , Luca Marinelli 2 , Christopher J. Hardy 2 , Dan W.
Rettmann 3 , Wei Sun 4 , Stephen Garnier 4 , Ersin Bayram 4 , Piergiorgio Masci 1 , Vincenzo
Positano 1 , Luigi Landini 5 , Massimo Lombardi 1
1 "G. Monasterio" Foundation, Pisa, Italy; 2 Global Research Center, General Electric, Niskayuna, NY, United
States; 3 Applied Science Laboratory, GE Healthcare, Rochester, MN, United States; 4 GE Healthcare,
Milwaukee, WI, United States; 5 Department of Information Engineering, University of Pisa, Italy
This study presents a new highly accelerated 3d saturation recovery first-pass perfusion using balanced steady state free precession
(Fiesta) pulse sequence. Saturation was carried out through a 8ms adiabatic BIR4 radio frequency pulse. Acquisition was carried out at