ELECTRONIC POSTER - ismrm

15:00 3711. Improved Simulation of 3D Flow Characteristics in a Pressure Controlled in Vitro
Model System
Ramona Lorenz 1 , Christoph Benk 2 , Jelena Bock 1 , Jan Korvink 3 , Michael Markl 1
1 Dept. of Diagnostic Radiology, University Hospital, Freiburg, Germany; 2 Dept. of Cardiovascular Surgery,
University Hospital, Freiburg, Germany; 3 Dept. of Microsystems Technology, IMTEK, Freiburg, Germany
In-vitro model systems provide a useful tool for the systematic evaluation of hemodynamic changes associated with geometric
vascular modifications. However, realistic in-vivo in-flow and boundary conditions are necessary for accurate flow simulations. This
paper presents a novel approach for an in-vitro model setup which includes a pulsatile pump chamber in combination with flexible and
monitored pressure control using an adjustable mock loop to simulate physiological pre- and after load conditions. In contrast to
measurements without pressure control an improved generation of qualitative and quantitative flow characteristics compared to invivo
flow conditions could be achieved.
Image Post-Processing
Hall B Monday 14:00-16:00 Computer 38
14:00 3712. Investigation of Myocardium Structure of Postinfarct Porcine Model Using
Superquadric Glyphs
Yin Wu 1,2 , Ed Xuekui Wu 2,3
1 Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Shenzhen,
Guangdong, China; 2 Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong,
Pokfulam, Hong Kong; 3 Dept. of Electrical and Electronic Engineering, The University of Hong Kong,
Pokfulam, Hong Kong
Previous DTI studies on infarcted LV myocardium structure usually explored myocardial fiber orientation, diffusivity or diffusion
anisotropies. In current study, superquadric glyphs were applied on infarcted porcine model. Diffusion tensor shape and laminar sheet
structure were examined for the first time to describe infarcted myocardium structural alteration. Results show that significant change
of diffusion tensor shape occurred in both infarct and adjacent regions. Apparent alteration of laminar sheet structure was observed in
adjacent and remote regions. The current study demonstrates the ability of superquadric glyphs to detect myocardium structural
degeneration and provides supplemental information for infarcted heart remodeling.
14:30 3713. Multiecho Dixon Fat and Water Separation Method for Diagnosing Pericardial
Disease
Amir H. Davarpanah 1 , Aya Kino 1 , Kirsi Taimen 1 , Philip Hodnet 1 , Jeremy Collins 1 ,
Cormac Farrelly 1 , Saurabh Shah 2 , Sven Zuehlsdorff 2 , James Carr 1
1 Department of Radiology, Cardiovascular Imaging, Northwestern University, chicago, IL, United States;
2 Siemens Medical Solutions, chicago, IL, United States
The VARPRO method (multi-echo gradient echo sequence with iterative fat/water decomposition reconstruction)for fat/water
separation performs better than the standard fat saturation protocol currently used at our institution. The water image from this method
presents with a more uniform fat suppression.
15:00 3714. Automated Evaluation of Left Ventricular Diastolic Function Using Velocity-
Encoded Magnetic Resonance Imaging: Conventional and New Parameters
Emilie Bollache 1 , Stéphanie Clément-Guinaudeau 2 , Ludivine Perdrix 3 , Magalie
Ladouceur 1,3 , Muriel Lefort 1 , Alain De Cesare 1 , Alain Herment 1 , Benoît Diebold 1,3 , Elie
Mousseaux 1,2 , Nadjia Kachenoura 1
1 INSERM U678, UPMC, Paris, France; 2 Radiology department, APHP, European Hospital Georges Pompidou,
Paris, France; 3 Echocardiography department, APHP, European Hospital Georges Pompidou, Paris, France
Phase-contrast (PC) Magnetic Resonance (MR) is not used in clinical routine to assess diastolic function, because of the lack of
automated analyses. Thus, our aim was to develop a process to automatically analyze PC data. Automated segmentation of PC images
and analysis of velocity and flow rate curves to derive diastolic parameters were developed and tested on 25 controls. Segmentation
was successful in all subjects. Our conventional parameters were consistent with those previously presented in literature and our new
parameters highly correlated with high prognosis value parameters. Our process may provide a valuable addition to the established
cardiac MR tools.
15:30 3715. Unsupervised and Reproducible Image-Based Identification of Cardiac Phases in
Cine SSFP MRI
Sotirios A. Tsaftaris 1,2 , Xiangzhi Zhou 2 , Richard Tang 2 , Rohan Dharmakumar 2
1 Electrical Engineering and Computer Science, Northwestern University, Evanston, IL, United States;
2 Radiology, Northwestern University, Chicago, IL, United States
It is particularly important for the evaluation of cardiac phase-resolved myocardial blood-oxygen-level-dependent (BOLD) MRI
studies, to robustly and reproducibly identify end-systolic (ES) and end-diastolic (ED). Most automated methods rely on identifying
the minimum and maximum of the blood pool area in the Left Ventricle chamber, but they are computationally intensive, susceptible
to noise, and require prior localization and segmentation of the chamber. The purpose of this work is to develop automated methods to