ELECTRONIC POSTER - ismrm

15:30 4569. Characterization of Cirrhotic Nodules with Gadoxetic Acid-Enhanced MR Imaging:
The Efficacy of Hepatocyte-Phase Imaging
Chen-Te Chou 1,2 , Ran-Chou Chen 2,3
1 Radiology, Chang-Hua Christian Hospital, Chang-Hua, Taiwan; 2 Biomedical Imaging and Radiological
Science, National Yang-Ming Medical University, Taipei, Taiwan; 3 Radiology, Taipei City Hospital, Taipei,
Taiwan
The study was to evaluate the efficacy of hepatocyte-phase imaging in characterization of focal hepatic lesions among cirrhotic liver
using gadoxetic acid enhanced MRI. Our results revealed SNRs/CNRs of HCC were significantly decreased in hepatocyte phase
(P0.05). Severe additional HCC were diagnosed by hepatocyte-phase
imaging. The diagnostic performance is significantly higher in the imaging set with hepatocyte-phase imaging (P=0.016). In
conclusion, combination of gadoxetic acid-enhanced dynamic study and hepatocyte-phase imaging could provide better diagnostic
performance than dynamic study only in characterization of focal liver lesion among cirrhotic liver.
Tuesday 13:30-15:30 Computer 92
13:30 4570. Gd-EOB-DTPA Enhanced MR Imaging of the Liver: Correlation with
Morphological Severity of Cirrhosis and Hepatic Parenchyma Enhancement at Hepatobiliary
Phase
Atsushi Higaki 1 , Tsutomu Tamada 1 , Akihiko Kanki 1 , Yasufumi Noda 1 , Hiroki Higashi 1 ,
Takenori Yamashita 1 , Katsuyoshi Ito 1
1 Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan
We evaluated the relationships between enhancement effects of liver parenchyma in hepatobiliary phase of gadolinium ethoxybenzyl
diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) enhanced MR imaging and MR imaging findings of cirrhosis change. Hepatic
parenchymal enhancement in the HP of Gd-EOB-DTPA enhanced MR imaging did not necessarily decrease according to the
morphological severity of cirrhosis. This fact may suggest that the hepatic uptake of Gd-EOB-DTPA depends on the preserved
hepatocytes function rather than the severity in morphologic changes in cirrhosis.
14:00 4571. Diffusion-Weighted MR Imaging Improves Sensitivity of Lesion Detection
Compared with Gadolinium Enhanced T1-Weighted Imaging in Patients with Suspected
Liver Metastases from Neuroendocrine Tumours.
Mark Ingram 1 , Toni Wallace 2 , Erica Scurr 2 , David J. Collins 2,3 , Val Lewington 4 , Dow-Mu
Koh 2
1 Department of Radiology, St George's Healthcare NHS Trust, Tooting, London, United Kingdom; 2 Department
of Radiology, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; 3 CRUK-EPSRC Cancer
Imaging Centre, Institute of Cancer Research, Sutton, Surrey, United Kingdom; 4 Department of Nuclear
Medicine, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
In patients with neuroendocrine liver metastases, imaging determination of the size and distribution of metastatic disease is of value as
it could influence the choice of therapy. We compared diffusion-weighted MR imaging (DW-MRI) and gadolinium-DTPA enhanced
MR imaging for the detection of focal liver lesions in patients with suspected liver metastases arising from neuroendocrine tumours.
DW-MRI was found to have a significantly higher diagnostic sensitivity (88%) compared with gadolinium-DTPA enhanced MR
imaging (77%) for lesion detection in this patient population (p = 0.001, McNemar test).
14:30 4572. How to Reduce So-Called Ringing Artifacts in Primovist-Enhanced MR Imaging
Akihiro Tanimoto 1 , Nobuya Higuchi 2 , Akihisa Ueno 2 , Shigeo Okuda 2
1 Department of Diagnostic Radiology, School of Medicine, Keio University , Tokyo, Japan; 2 Department of
Diagnostic Radiology, School of Medicine, Keio University, Tokyo, Japan
So-called gringing artifactsh are often associated with Primovist-enhanced dynamic MR imaging, aggravating the diagnosis for
focal hepatic lesions. To analyze the cause of this phenomenon, various scan and data acquisition parameters were tested using a
newly created simulation software on the personal PC. The simulation study revealed that square matrices, short scanning time, slow
infusion rate, and sequential view ordering were effective measures to reduce the artifacts. These results were confirmed in the
clinical practice of Primovist-enhanced MR imaging.
15:00 4573. Initial Clinical Experience with FRFSE Triple Echo Dixon (FRFTED) for Breath-
Hold Fast Dixon Abdominal MR Imaging
Russell Norman Low 1,2 , Jingfe Ma 3 , Neeraj Panchal 1,2
1 Sharp and Children's MRI Center, San Diego, CA, United States; 2 San Diego Imaging, San Diego, CA, United
States; 3 Department of Imaging Physics, The University of Texas MD Anderon Cancer Center, Houson, TX,
United States
This study evaluates a prototype breath hold fast recovery fast spin echo (FSE) based Dixon pulse sequence that provides superior fat
suppression less sensitive to magnetic field inhomogeneities.