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therapies. MRI characteristics of triple negative breast cancer could assist pretreatment planning and prognosis assessment. We<br />

evaluated MRI and clinicopathologic features of triple negative breast cancer, and compared them with those of non triple negative<br />

breast cancer.<br />

15:00 4561. Multiparametric MR Measurement of Menstrual Variation in the Breast<br />

Sungheon Kim 1 , Linda Moy 1 , Malcolm C. Pike 2 , Anne Zeleniuch-Jacquotte 3 , Tess<br />

Clendenen 4<br />

1 Center for Biomedical Imaging, Radiology, NYU School of Medicine, New York, NY, United States;<br />

2 Preventive Medicine, USC Keck School of Medicine, Los Angeles, CA, United States; 3 Environmental<br />

Medicine, NYU School of Medicine, New York, NY, United States; 4 Epidemiology, NYU School of Medicine,<br />

New York, NY, United States<br />

The purpose of this study was to develop a multiparametric MRI method to investigate magnitude and timing of various breast<br />

changes during the menstrual cycle. Five healthy premenopausal women were scanned once a week for four weeks. T2, ADC, and<br />

magnetization transfer rate were measured. T2 gradually increased throughout the cycle and was 5% higher in the menstrual phase<br />

than the follicular phase. In contrast, the median ADC was highest in the luteal phase (15% greater than the follicular phase) and<br />

began to decline during menses. The MTR was about 4% lower in the menstrual phase than the follicular phase.<br />

Fetal & Female Pelvis<br />

Hall B Thursday 13:30-15:30 Computer 91<br />

13:30 4562. Time-Resolved MR Angiography in the Detection of Ovarian Venous Reflux<br />

Dal Mo Yang 1 , Dong Ho Lee 2 , Dong Wook Sung 2 , Geon-Ho Jahng, Chang Woo Ryu<br />

1 Radiology, East-West Neo Medical Center, Kyung Hee University, Seoul, Korea, Republic of; 2 Radiology,<br />

Kyung Hee University Hospital<br />

The purpose of this study was to compare the diagnostic accuracy of time-resolved MR angiography with that of conventional<br />

angiography for detection of ovarian venous reflux, which aid for a diagnosis of pelvic venous congestion. Retrospective analysis was<br />

performed with 19 consecutive patients who underwent time-resolved MR angiography and conventional angiography. There was no<br />

significant difference between time-resolved MR angiography and conventional angiography for detection of ovarian venous reflux (P<br />

> 0.05). The sensitivity, specificity, and diagnostic accuracy of time-resolved MR angiography were found to be 93.5%, 66.7%, and<br />

89.5%, respectively. Time-resolved MR angiography is helpful for diagnosis of pelvic venous congestion.<br />

14:00 4563. Magnetic Resonance Imaging and Ultrasonography in Diagnosis of Pelvic Vein<br />

Thrombosis During Pregnancy<br />

Michael R. Torkzad 1 , Katarina Bremme 2 , Margareta Hellgren 3 , Maria J. Eriksson 4 , Anna<br />

Hagman 5 , Trine Jörgensen 2 , Kent Lund 4 , Gunnel Sandgren 6 , Lennart Blomqvist 7 , Peter<br />

Kälebo 8<br />

1 Radiology Department, Uppsala University Hospital, Stockholm, Sweden; 2 Karolinska Institutet, Woman and<br />

Child Health, Stockholm, Sweden; 3 The Sahlgrenska Academy, University of Gothenburg, Institute for the<br />

Health of Women and Children, Gothenburg, Sweden; 4 Karolinska Institutet, Department of Clinical<br />

Physiology, Stockholm, Sweden; 5 The Sahlgrenska Academy, Institute for the Health of Women and Children,<br />

Gothenburg, Sweden; 6 Sahlgrenska University Hospital/Östra, Department of Clinical Physiology, Gothenburg,<br />

Sweden; 7 Department of Diagnostic Radiology, Karolinska University Hospital Solna, Department of<br />

Diagnostic Radiology, Stockholm, Sweden; 8 Sahlgrenska University Hospital/Östra, Department of Radiology,<br />

Gothenburg, Sweden<br />

Purpose: The agreement between ultrasonography and magnetic resonance imaging (MRI) in diagnosing the extent of pelvic deep vein<br />

thrombosis (DVT) during pregnancy was measured. Materials and methods Pelvic veins of 27 pregnant women with DVT were<br />

examined with ultrasound and MRI. Results: Three cases (11.5%) of DVT in the pelvic veins were shown only on MRI. MRI was able<br />

to detect highr thrombus extension in 65% of cases. Proportion of agreement (ê) between ultrasound and MRI for DVT in individual<br />

veins was 0.33 (95% CI 0.27-0.40, i.e. fair agreement). Conclusion: MRI could be essential in diagnosis of pelvic DVT during<br />

pregnancy.<br />

14:30 4564. Assessment of Placental Blood Flow Using a Navigator Echo Respiratory Gated<br />

Parallel Imaging Technique at 1.5 T<br />

Loredana Sorina Truica 1 , Ian Cameron, 1,2 , Leonard I. Avruch 2 , Andre Gruslin 2<br />

1 Carleton University, Ottawa, ON, Canada; 2 The Ottawa Hospital, Ottawa, ON, Canada<br />

IVIM measurements of normal placenta at 1.5 T using a respiratory triggered DW_SS_EPI sequence are reported. Improvements in<br />

the acquisition and analysis techniques used in this study allowed us to obtain more consistent results for the perfusion fraction, f, the<br />

diffusion coefficient, D, and the pseudo-diffusion coefficient, D*, than previous studies. Parameter maps of D and f were reflective of<br />

placental structure and composition. Such maps can be useful tools in identifying tissue differences and give important insight into the<br />

placental hemodynamic systems. This technique could become instrumental in the assessment and management of abnormal<br />

pregnancies.

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