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14:30 4612. MRI Assessment of Distal Airway Heterogeneity for the Early Detection of Airway Disease with Normal Spirometry Ding Xia 1 , Elan J. Grossman 1 , Ke Zhang 1 , Abram Voorhees 2 , K I. Berger 3 , R M. Goldring 3 , B W. Oppenheimer 3 , J Reibman 3 , W N. Rom 3 , L Rogers 3 , A Helwig 3 , L Daugherty 4 , Jian Xu 1 , Kelly A. Mcgorty 1 , Qun Chen 1 1 Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, United States; 2 Siemens Medical Solutions, Malvern, PA, United States; 3 Department of Medicine, NYU School of Medicine, New York, United States; 4 Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States Clinical-pathologic correlation between patient illness and pulmonary disease is difficult to determine when airway abnormalities are localized only to distal airways of the lungs. The purpose of this study is to establish quantitative regional measurements of heterogeneity for distal airway dysfunction based on a tissue tracking MRI technique and apply them to early diagnosis of obstructive airway disease. Results show that in subjects with suspected distal airway disease MRI indicators of mean regional airflow are reduced despite presentation of normal spirometry. Thus, assessment of regional lung function by MRI may be a useful tool for early detection of airway disease. 15:00 4613. Sensitivity of Viscosity and Elasticity in Preserved Pig Lung by Magnetic Resonance Elastography Roberta Santarelli 1 , Xavier Maître 1 , Ralph Sinkus 2 , Luc Darrasse 1 1 Imagerie par Résonance Magnétique et MultiModalités (UMR8081), Univ Paris-Sud, CNRS, Orsay, France; 2 Institut Langevin (UMR 7587), ESPCI, Univ Denis Diderot, CNRS, Paris, France Viscoelastic properties of lungs participate in the organ basic function. Their exploration in vivo is not attainable. Hyperpolarised helium-3 MR-elastography on lungs has been demonstrated in vivo. This new technique ex vivo quantitatively evaluated the comparison between helium-3 and hydrogen MRE: the fluid/structure coupling was found to be strong, validating helium-3 lung MRE as a consistent tool for lung exploration. This work focuses on viscoelastic properties behaviour of hydrogen MRE, applied on the preserved pig lung inflated at different volumes: performance of wavelength, elasticity, and viscosity distribution is discernible throughout the inner area and the outer peripheries of the lungs Obesity & Metabolism Hall B Monday 14:00-16:00 Computer 95 14:00 4614. Abdominal Adipose Tissue Distribution: Regional Differences Min-Hui Cui 1 , Jong Hee Hwang 1 , Vlad Tomuta 1 , Daniel T. Stein 1 1 Albert Einstein College of Medicine, Bronx, NY, United States Fifty-eight non-diabetic subjects with a wide range of BMI were studied to evaluate the regional differences of SAT and VAT distribution and the correlations of them with intrahepatic lipid, plasma triglyceride, glucose and FFA levels. Both lean and overweight/obese subjects have most SAT in lower abdomen. However, lean subjects have more VAT while overweight/obese subjects have less VAT in lower abdomen. The relationships between SAT and VAT from different abdominal regions in the lean and overweight/obese subjects with IHL, TG and glucose are also different. Thus conclusions based on one specific AT region should be interpreted with cautions. 14:30 4615. Whole Body Fat Water Imaging at 3 Tesla Using Multi-Echo Gradient Echo E. Brian Welch 1,2 , Johan Berglund 3 , Heidi J. Silver 4 , Kevin D. Niswender 5 , Morten Bruvold 6 , Joel Kullberg 3 , Lars Johansson 3 , Malcolm J. Avison 1 1 Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States; 2 MR Clinical Science, Philips Healthcare, Highland Heights, OH, United States; 3 Department of Radiology, Uppsala University, Uppsala, Sweden; 4 Vanderbilt Center for Human Nutrition, Vanderbilt University Medical Center, Nashville, TN, United States; 5 Vanderbilt Diabetes Research and Training Center, Vanderbilt University Medical Center, Nashville, TN, United States; 6 MR Clinical Science, Philips Healthcare, Best, Netherlands The potential of whole body MRI for visualizing adipose tissue distribution has long been recognized. More recently, multi-gradientecho MR acquisitions have been successfully used at 1.5 Tesla to quickly acquire whole-body data sets. Automated segmentation and quantification of such whole-body fat images into subcutaneous and visceral adipose tissue compartments shows great promise as a tool in studies of obesity and other metabolic syndrome diseases such as diabetes. Most whole-body fat-water imaging has been performed at 1.5 Tesla. However, the availability and prevalence of higher strength 3 Tesla scanners, especially in research settings, justifies the pursuit of robust multi-gradient-echo sequences designed to operate at 3 Tesla. Here we present initial results of a 3T multi-gradient echo whole-body fat-water sequence.
15:00 4616. Rapid, Multi-Slice Fat Water Separated Imaging for Mapping Body Fat Peter Kellman 1 , Diego Hernando 2 , Saurabh Shah 3 , Z-P Liang 2 , David A. Bluemke 1 , Andrew E. Arai 1 1 National Institutes of Health, Bethesda, MD, United States; 2 University of Illinois, Urbana, IL, United States; 3 Siemens Medical Solutions, Chicago, IL, United States A rapid multi-slice fat/water separated imaging protocol has been developed for mapping body fat with application to obesity studies. The method combines a 3-echo GRE acquisition and parallel imaging to scan the abdomen and chest in
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ELECTRONIC POSTER Cartilage Hall B
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14:00 3173. Sodium MRI: A Reproduci
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15:00 3182. Comparison of Short Ech
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15:00 3191. The Application of Magn
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to unity. Conversely, in trabecular
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determination of perfusion and perm
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unique ability of UTE MRI to direct
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throughout the maturation process,
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lipoatrophy with decreased of the l
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Tuesday 13:30-15:30 Computer 6 13:3
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15:00 3267. Dynamic Hyperpolarized
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Hall B Monday 14:00-16:00 Computer
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hyperpolarized for use as a metabol
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15:30 3295. 1 H Decoupled 13 C MRS
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use of short and high bandwidth adi
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14:30 3325. Modeling of 3-Dimension
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Thursday 13:30-15:30 Computer 11 13
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14:00 3345. An Optimized T1nom Appr
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Increasing spatial resolution is ad
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14:30 3362. NMR Plasma Profiling of
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Spectroscopic Localization & Imagin
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total scan time and remove the spac
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Tuesday 13:30-15:30 Computer 18 13:
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15:00 3415. Modeling Neuronal Curre
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14:30 3425. A Randomized Global Sig
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15:00 3435. Investigating the Feasi
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BOLD activation within parenchymal
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15:00 3455. Understanding the Limit
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14:00 3465. Effect of EEG Electrode
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14:30 3486. Magnetization Transfer
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15:00 3506. DMN Is Affected Incongr
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the brain edge. Upon detrending thi
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healthy controls using empathy for
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14:30 3534. Single Word Reading in
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activates superior colliculus and l
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Myocardial Function Human & Experim
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14:30 3562. Cardiac Torsion and Str
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14:30 3582. Early Diastolic Strain-
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Non-Cartesian k-space trajectories
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14:30 3601. Analysis of Cardio-Resp
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15:00 3611. An Optimal Physiologic
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depending on its linear or centric
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3Tesla using a 32 channel cardiac c
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States; 5 Chemistry & Chemical Engi
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similar set of fully sampled data.
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demonstrated 35% improvement in blo
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15:00 3679. Toward a Novel Implanta
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14:30 3697. Time-Resolved Spin-Labe
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and 13 patients, including peak and
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facilitate in the robust and reprod
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accurate quantification. The -goal
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and then auto-transplanted back to
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14:30 3755. The Use of Cellular MRI
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sampling patterns which are tailore
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with potential for improving diagno
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14:30 3795. Targeted Travelling Wav
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14:30 3806. A 8 Channel TX/RX Decou
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15:00 3816. A 7T ‘Capless’ Tran
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14:30 3827. A Mechanically Tuned 8-
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Receive Arrays Hall B Monday 14:00-
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15:00 3848. A Combined Solenoid-Sur
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the past and thus yields more reali
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14:30 3870. SAR Sensitivity to Phas
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heart between 20 and 40°C. As a re
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challenges for its simultaneous com
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experimental results showed the bes
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14:30 3922. Six Layers Stripline RF
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14:30 3933. Eigenmode Analysis of E
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and a relaxed fixed point iteration
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15:00 3955. Improved PET Data Quant
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15:00 3966. Diffusion Properties of
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14:00 3985. Development of a WM Atl
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existing parallel imaging and parti
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15:00 4016. Application of Rotation
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14:30 4026. Classification of Non-G
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15:00 4036. Sensitivity of Motion E
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14:00 4046. Effects of Hypercapnia
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Arterial Spin Labeling: Methods Hal
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14:30 4066. Accounting for Dispersi
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using both methods but the differen
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estimates. Differences in delays an
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angioplasty balloon in the aorta. T
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14:30 4134. Optimal Ultrasonic Focu
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14:30 4144. TMAP @ IFE - A Framewor
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14:30 4164. Transmit Power Optimiza
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15:00 4173. Magnetic Resonance Micr
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Cell Tracking II Hall B Monday 14:0
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14:30 4192. Quantification of Cell
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15:30 4201. Characterisation of a L
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14:30 4220. Prolonged and Homogenou
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are not sensitive to early abnormal
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14:30 4240. DCE-MRI and DW-MRI in C
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15:00 4249. Are Behavioural Symptom
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were observed from the preCG and IC
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14:00 4267. Absolute Quantification
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Vergata"; 6 Cognition and Cognitive
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14:00 4283. Differentiation of Radi
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14:00 4291. Influence of Combined F
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secular-T2 peaks revealed significa
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Multiple Sclerosis I Hall B Monday
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14:30 4320. Profile-Based Cortical
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independent predictors of disabilit
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14:30 4364. Measurement of Iron Con
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15:00 4846. The Assessment of Early
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Our results indicate that the propo
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Tuesday 13:30-15:30 Computer 111 13
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egularizing terms that may affect t
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times due to the need of additional
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proposed homotopic L0 minimization
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15:00 4910. Auto-Calibrated Paralle
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14:30 4921. Sparse Parallel Transmi
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1 Imaging Division, UMC utrecht, Ut
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Wednesday 13:30-15:30 Computer 116
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frequency k-space data are processe
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cylinders trajectory and have imple
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still requires scan durations not a
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15:00 5006. A T 2 * Selective Highe
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14:00 5016. High Spatial and Tempor
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perform the AC of the SPECT data. T
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15:30 5058. Reducing Ghosting in EP
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Wednesday 13:30-15:30 Computer 124
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egularization parameter is adapted
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14:00 5108. Correction Algorithm fo
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IDEAL knee MRI data is proposed. Va
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14:30 5129. Design of Iron Sensitiv
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