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ELECTRONIC POSTER - ismrm

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14:30 3779. Balanced SSFP Spin-Labeled Angiography Using Sparse Data: Optimization and<br />

Application to Supraaortic Vessels<br />

Ioannis Koktzoglou 1 , Philip Hodnett, 1,2 , Erik Offerman 1 , Robert Edelman 1<br />

1 Radiology, NorthShore University HealthSystem, Evanston, IL, United States; 2 Northwestern University,<br />

Chicago, IL, United States<br />

Arterial spin-labeled MRA using a balanced steady-state free precession is limited by flow artifacts in the setting of luminal<br />

narrowing. In a stenotic flow phantom, we show that these artifacts can be minimized with the use of abbreviated echo trains made<br />

possible with the use of parallel imaging acceleration and partial Fourier acquisition, and subsequently apply the technique in<br />

volunteers and patients.<br />

15:00 3780. Magnetic Resonance Imaging Measurements Predict Need for Intervention in<br />

Patients Post Ross Procedure<br />

Anna Lakoma 1 , James C. Carr 1<br />

1 Department of Radiology, Northwestern University, Chicago, IL, United States<br />

MRI derived pulmonary circulation parameters best predict need for future intervention in patients post Ross procedure.<br />

Wednesday 13:30-15:30 Computer 42<br />

13:30 3781. Accelerated Time Resolved Inflow with 3D Multi-Echo Radial Trajectories<br />

Kevin M . Johnson 1 , Oliver Wieben 1,2 , Patrick Turski 2 , Charles Mistretta 1<br />

1 Medical Physics, University of Wisconsin - Madison, Madison, WI, United States; 2 Radiology, University of<br />

Wisconsin - Madison, Madison, WI, United States<br />

Arterial spin labeling (ASL) sequences which utilize tagging schemes to images the flow of blood have emerged as effective<br />

techniques for the non-contrast angiography; however, these techniques typically suffer from long acquisition times, sensitivity to tag<br />

delay parameters, and uncertain performance in cases of complex flow . To mitigate these errors, we investigate the utilization of<br />

highly accelerated, dynamic inflow imaging utilizing efficient, short TR 3D radial bSSFP sequences.<br />

14:00 3782. Non-Contrast Enhanced Pulmonary Vein MRA with Compressed Sensing<br />

Mehmet Akçakaya 1,2 , Peng Hu 2 , Vahid Tarokh 1 , Warren J. Manning 2 , Reza Nezafat 2<br />

1 Harvard University, Cambridge, MA, United States; 2 Beth Israel Deaconess Medical Center, Harvard Medical<br />

School, Boston, MA, United States<br />

Non-contrast pulmonary vein (PV) MR angiography (MRA) is an alternative to the clinical contrast-enhanced technique. We have<br />

recently developed a non-contrast PV MRA technique using a sagittal selective inversion pulse. However, the resulting acquisition<br />

time is significantly longer than breath-hold contrast-enhanced technique. In this study, we investigate the feasibility of using<br />

compressed sensing for accelerating data acquisition in non-contrast PV MRA. We use a distributed compressed sensing technique to<br />

reconstruct separate coil images simultaneously. We show that this reconstruction yields good results even at high rates (x10).<br />

14:30 3783. Non-Contrast Inversion Recovery Balanced Ssfp Mra of the Abdominal Aorta at<br />

3T: Predicting Optimal Inversion Times by Blood Velocity Measurement<br />

Iliyana Plamenova Atanasova 1,2 , Ruth P. Lim 1 , Hua Guo 1 , Daniel Kim 1 , Pippa Storey 1 ,<br />

Kellyanne McGorty 1 , Andrew Laine 2 , Vivian S. Lee 1<br />

1 Department of Radiology, New York University, New York, United States; 2 Columbia University, New York,<br />

United States<br />

3D non-enhanced balanced steady-state free precession MRA with a slab-selective inversion (IR SSFP) has demonstrated promise for<br />

renal artery evaluation at 1.5T. With proper selection of inversion times (TI), the technique can be adopted for coronal imaging of the<br />

abdominal aorta with comprehensive superior-inferior coverage at 3T. We propose a method for subject-specific calculation of TI<br />

based on arterial blood velocities. Our results illustrate that visualization of the aortoiliac vessels using IR SSFP varies considerably<br />

across subjects depending on flow velocities. Thus, measuring aortic velocities prior to MRA enables an examination tailored to the<br />

patient’s physiology for improved arterial visualization.<br />

15:00 3784. MRI Determined Carotid Artery Flow Velocities and Wall Shear Stress in a Mouse<br />

Model of Vulnerable and Stable Atherosclerotic Plaque<br />

Gustav Jacob Strijkers 1 , Glenda S. van Bochove 1 , Roel Straathof 1 , Rob Krams 2 , Klaas<br />

Nicolay 1<br />

1 Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven,<br />

Netherlands; 2 Department of Bioengineering, London Imperial College, London, United Kingdom<br />

We report here on the pre-clinical MRI characterization of an apoE-/- mouse model of stable and vulnerable carotid artery<br />

atherosclerotic plaques, which were induced by a tapered restriction (cast) around the artery. Specific focus was on the quantification<br />

of flow velocities and wall shear stress (WSS), which are considered key players in the development of the plaque phenotype.

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