ELECTRONIC POSTER - ismrm

Thursday 13:30-15:30 Computer 42
13:30 3785. A Novel 3D Time-Of-Flight MRA with Optimized Partial Saturation Recovery 3D-
FLASH
Yutaka Natsuaki 1 , Randall Kroeker 2 , Gerhard Laub 3
1 Siemens Medical Solutions, Los Angeles, CA, United States; 2 Siemens Medical Solutions, Winnipeg,
Manitoba, Canada; 3 Siemens Medical Solutions, San Francisco, CA, United States
One of the major drawbacks with 3DTOF is the inplane flow saturation, where the fresh inflow enters the imaging volume and gets
saturated by the imaging RF pulses. This is particularly problematic when the inflow vessels are perpendicular to the slice direction
(e.g. vertebral arteries), and this may result in signal loss of the blood vessels. The current work proposes a novel approach to the
magnetization prepared 3D TOF MRA with the partial saturation recovery (SR) 3D-FLASH. The optimization strategies and initial
results with improved visualization of vertebral arteries are presented.
14:00 3786. 3D Non-Contrast MRA of Lower Extremities Using Balanced SSFP with Flow-
Sensitive Dephasing (FSD) at 3T
Hua Guo 1 , Iliyana Atanasova 1,2 , Ruth P. Lim 1 , Pippa Storey 1 , Jian Xu 3 , Qun Chen 1 ,
Henry Rusinek 1 , Zhaoyang Fan 4 , Debiao Li 4 , Vivian S. Lee 1
1 Department of Radiology, New York University School of Medicine, New York, NY, United States;
2 Columbia University, New York, NY, United States; 3 Siemens Medical Solutions USA, Inc., MR R&D
Collaboration, New York, United States; 4 Departments of Radiology and Biomedical Engineering,
Northwestern University, Chicago, IL, United States
Flow-sensitive dephasing prepared balanced steady state free precession (FSD-bSSFP) has been proposed as a non-contrast MRA
technique for the lower extremities at 1.5T. However, its application at higher magnetic fields is hindered by poor B0 and B1
homogeneities. As a result, the background signal cannot be completely suppressed. In this work, we investigated the performance of
B1-insensitive adiabatic RF pulses for FSD preparation to improve non-contrast MRA with FSD-bSSFP at 3T. The results
demonstrate that the approach is less B1-sensitive than with conventional hard RF pulses, thus providing better background signal
suppression and more reliable MRA images at 3T.
14:30 3787. MRI and Micro-CT Evaluate the Effect of VEGF in a Rabbit Femoral Artery
Chronic Total Occlusion
Xiuling Qi 1 , Aaron Teitelbaum 1 , Kevan Anderson 1 , Nigel Munce 1 , Beiping Qiang 1 , Ronen
Jaffe 1 , Michelle Ladouceur-Wodzak 1 , Bradley H. Strauss 1 , Graham A. Wright 1
1 Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
Synopsis: Revascularization in an arterial chronic total occlusion (CTO) could improve the prognosis. We evaluated the effect of
injecting vascular endothelial growth factor (VEGF) into a CTO in a femoral artery of rabbit using in vivo MRI and ex-vivo micro-
CT. Thirteen rabbit were divided randomly into control and VEGF groups. The blood volume changes in CTO pre and post
interventions were determined. Results indicated by both MRI and micro-CT that the VEGF significantly increased the formation of
microvessels within CTO. Our study also demonstrated that MRI is a feasible method to assess the new blood vessel growth in CTO
tissue.
15:00 3788. Noncontrast MRA Using Spiral Refocused Turbo Spin Echo
Samuel W. Fielden 1 , Hao Tan 1 , John P. Mugler III 1,2 , Christopher M. Kramer 2,3 , Craig H.
Meyer 1,2
1 Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 2 Radiology, University of
Virginia, Charlottesville, VA, United States; 3 Medicine, University of Virginia, Charlottesville, VA, United
States
rTSE hybridizes the increased signal provided by the 180° refocusing RF pulses of RARE and the better flow performance of the
fully-refocused gradients and phase alternation of balanced SSFP. Here, we apply the principles of rTSE with spiral readout gradients
in order to improve the data acquisition efficiency of the sequence while increasing the echo spacing to provide improved artery-vein
contrast.
Antennas & Waves
Hall B Monday 14:00-16:00 Computer 43
14:00 3789. Traveling Wave MRI for the Acquisition of Reference Images for Parallel Imaging
at the Carotid Artery at 7T - Proof of Concept
Wouter Koning 1 , Hugo Kroeze, 2 , Bart Leo van de Bank, Vincent O. Boer, Cornelis A. van
den Berg, Jaco J. Zwanenburg, Peter R. Luijten, Dennis W. Klomp
1 Radiology, UMC Utrecht, Utrecht, Netherlands; 2 MTKF
In high field MRI, acceleration with parallel imaging in MRI can be a challenge as homogeneous reference scans are difficult to
obtain. Traveling wave MRI can be applied for the acquisition of reference images. This enables acceleration with parallel imaging