ELECTRONIC POSTER - ismrm

Wednesday 13:30-15:30 Computer 36
13:30 3688. 3D Flow-Insensitive Vessel Wall Imaging Using T2PREP PSIR with SSFP
Jingsi Xie 1 , Xiaoming Bi 2 , Zhaoyang Fan 1 , Himanshu Bhat 1 , Saurabh Shah 2 , Sven
Zuehlsdorff 2 , Debiao Li 1
1 Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, United States;
2 Siemens Healthcare, Chicago, IL, United States
This work develops a 3D flow-insensitive technique for peripheral vessel wall imaging.
14:00 3689. The Value of Carotid Plaque MRI in the Selection of Choosing Stent-Treatment for
Carotid Atherosclerosis Patients
Yan Song 1 , Cheng Zhou, Min Chen, Nan Luo, Jiachun Liu, Lijun Wang, Yuan Fu,
Xiangyang Ma 2 , Chun Yuan 3
1 Department of Radiology, Beijing Hospital, Beijing, China; 2 Philips Global Clinical Research Board, Greater
China Region; 3 Department of radiology, University Washington, Seattle, United States
The purpose was to evaluate the efficiency of carotid plaque MRI in stent-treatment decision for patients with carotid atherosclerosis
comparing with DSA. A total of 17 symptomatic and 37 asymptomatic carotid arteries were evaluated by MRI and DSA. Images were
evaluated for luminal stenosis and fibrous cap (FC) rupture, and the stent treatment decision was based on these criterions. Intraplaque
hemorrhage and calcification were also evaluated by MRI. The result was that MRI was superior to DSA in determining stent
treatment, especially for asymptomatic patients with carotid artery narrowing of less than 70% for its ability to detect FC rupture.
14:30 3690. Comparison of Direct Thrombus Imaging to Multi-Contrast MRI for Assessment of
Carotid Atheroma
Victoria Eleanor Louise Young 1 , Umar Sadat 1 , Andrew J. Patterson 1 , Martin J. Graves 1,2 ,
Tjun Y. Tang 1 , Peter J. Kirkpatrick 3 , Jonathan H. Gillard 1
1 University Department of Radiology, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom;
2 Department of Medical Physics, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom;
3 Department of Neurosurgery, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom
Multi-contrast MRI is used for detection of complex carotid plaque, however, it is time consuming. Direct thrombus imaging (DTI)
has been used previously to detect intraplaque haemorrhage. The aim of this study was to assess whether DTI could be used
independent of other sequences to demonstrate complex disease. 55 patients with carotid stenosis (>30%) were imaged at 1.5T using a
4 channel phased-array carotid coil. Independent observers reviewed the multi-contrast imaging and DTI separately. DTI was found to
be highly sensitive/specific for detecting complex plaque. DTI can be used independent of other imaging to identify complex plaque.
15:00 3691. Large Field-Of-View Submillimeter Isotropic Resolution Bilateral Peripheral Vessel
Wall MRI Using 3D Fast Spin Echo with Flow-Insensitive Blood Suppression at 3 Tesla
Thanh D. Nguyen 1 , Keigo Kawaji 2 , Pascal Spincemaille 1 , Martin R. Prince 1 , Yi Wang 1,2
1 Radiology, Weill Cornell Medical College, New York, NY, United States; 2 Biomedical Engineering, Cornell
University, Ithaca, NY, United States
Black blood (BB) MRI can be used to characterize vessel wall and quantify atheresclerotic plaque burden in patients with peripheral
vascular disease. T2prep inversion recovery (T2IR) has been shown to provide flow-insensitive BB contrast for 2D peripheral vessel
wall MRI at 1.5T at the cost of reduced wall SNR The aim of this study is to achieve a considerable increase in T2IR BB imaging
efficiency to obtain large field-of-view bilateral peripheral coverage with sub-millimeter isotropic resolution in reasonable scan time
using SNR-efficient volumetric 3D fast spin echo acquisition at 3T. The developed sequence was capable of providing large
volumetric coverage, excellent arterial and venous blood suppression and fat suppression, as well as good vessel wall visualization in
healthy volunteers.
Thursday 13:30-15:30 Computer 36
13:30 3692. Improved Human Carotid Intraplaque Hemorrhage Imaging Using a Slab-Selective
Phase-Sensitive Inversion-Recovery (SPI) Sequence
Jinnan Wang 1 , Marina S. Ferguson 2 , Niranjan Balu 2 , Chun Yuan 2 , Thomas S.
Hatsukami 2 , Peter Boernert 3
1 Clinical Sites Research Program, Philips Research North America, Seattle, WA, United States; 2 University of
Washington; 3 Philips Research Europe
Intraplaque hemorrhage (IPH) plays a critical role in the evolution of carotid atherosclerotic disease. In this study, a Slab-selective
Phase-sensitive Inversion-recovery (SPI) technique, which combines both phase sensitive (PS) imaging and a specially designed IR
turbo field echo (TFE) sequence, is proposed to improve the IPH contrast and blood suppression efficiency in human carotid IPH
imaging. Significantly improved IPH contrast and blood suppression were found in the in vivo atherosclerotic patient scanning.