ELECTRONIC POSTER - ismrm

facilitate in the robust and reproducible evaluation of cardiac phase-resolved myocardial BOLD MRI through identification of ES and
ED images.
Tuesday 13:30-15:30 Computer 38
13:30 3716. Estimation of LV Function from Navigator Triggered, Real-Time Cardiac Cine
Steady-State Free Precession (SSFP) Imaging
Amol Pednekar 1 , Benjamin Cheong 2 , Raja Muthupillai 2 , Claudio Arena 2
1 Philips Healthcare, Cleveland, OH, United States; 2 Diagnostic and Interventional Radiology, St. Luke's
Episcopal Hospital, Houston, TX, United States
We propose an integrated real-time data acquisition and retrospective post-processing strategy to estimate parameters characterizing
global function of the left ventricle. Our initial evaluation of feasibility of this approach in normal subjects shows that slice-by-slice
LV volumes estimated using the real-time cine imaging approach are comparable to the LV volumes obtained using conventional,
breathhold cardiac cine SSFP techniques. The combination of respiratory navigator triggering, real-time unsegmented SSFP cine
imaging, and integrated retrospective automated processing may make this approach particularly useful in patients with severe
arrhythmias, and/or severely compromised respiratory function.
14:00 3717. ShMOLLI: Shortened Modified Look Locker Inversion Recovery for Cardiac T1
Mapping – from Theory to Normal Human Myocardium
Stefan K. Piechnik 1 , Vanessa M. Ferreira 2 , Erica Dall'Armellina 2 , Lowri E. Cochlin 3 ,
Stefan Neubauer 2 , Matthew D. Robson 2
1 Cardiovascular Medicine, OCMR, Oxford University , Oxford, Oxfordshire, United States; 2 Cardiovascular
Medicine, OCMR, Oxford University, Oxford, Oxfordshire, United States; 3 Dept of Physiology, Anatomy and
Genetics, Oxford University, Oxford, Oxfordshire, United States
We propose a cardiac T1-mapping method based on sequential Look-Locker measurements with conditional reconstruction of
incomplete recovery periods. This new method assures that robust T1 mapping can be achieved in a 9 heartbeat breath-hold with
accuracy comparable to existing methods.
14:30 3718. Preferential Patterns of Myocardial Iron Deposition by Multislice Multiecho T2*
CMR in Thalassemia Major Patients.
Antonella Meloni 1 , Vincenzo Positano 1 , Alessia Pepe 1 , Pasquale Pepe 1 , Maria Chiara
Dell'Amico 1 , Cristina Salvatori 1 , Petra Keilberg 1 , Gianluca Valeri 2 , Eliana Cracolici 3 ,
Pier Paolo Bitti 4 , Angelo Zuccarelli 5 , Maria Filomena Santarelli 1 , Massimo Lombardi 1
1 MRI Lab, “G. Monasterio Foundation” and Institute of Clinical Physiology, CNR, Pisa, Italy; 2 Azienda
Ospedaliero-Universitaria Ospedali Riuniti "Umberto I-Lancisi-Salesi", Ancona, Italy; 3 Policlinico "Paolo
Giaccone" , Palermo, Italy; 4 Dipartimento dei Servizi - P. O. San Francesco, Nuoro, Italy; 5 Centro trasfusionale
e di microcitemia - Ospedale civile, Olbia, Italy
Multislice multiecho T2* MRI allows quantification of iron overload in the whole myocardium. A preferential pattern of iron store in
anterior and inferior regions appears to be present in thalassemia major patients with severe and mild-moderate iron overload. The
preserved pattern between the groups prevents attributing this datum to additive susceptibility artefacts, which are negligible in
heavily iron-loaded patients. A segmental T2* CMR approach could identify early iron deposit, useful for tailoring chelation therapy
and preventing myocardial dysfunction in the clinical setting.
15:00 3719. RV Function from Cine MRI Using Contour Propagation
Wei Feng 1 , Himanshu Gupta 2 , Steven Lloyd 2 , Louis Dell'Italia 2 , Thomas S. Denney Jr 3
1 Biomedical Engineering, MRI Institute, Detroit, MI, United States; 2 Division of Cardiovascular Disease,
University of Alabama at Birmingham, Birmingham, AL, United States; 3 Electrical Engineering, Auburn
University, Auburn, AL, United States
This abstract presents a method for computing right-ventricular volume-versus-time curves and peak ejection and filling rates from
standard cardiac cine MRI. The method uses RV contours drawn semi-automatically near end-diastole and end-systole and propagates
them to the remaining time frames via a non-rigid registration technique. The propagated contours are validated by comparing them
to contours manually drawn by a cardiologist with Level 3 training. In addition, peak ejection and filling rates computed from both
manually-drawn and propagated contours are compared.
Wednesday 13:30-15:30 Computer 38
13:30 3720. 4D Right Ventricular Strain in Pulmonary Hypertension and Normals
Bharath Ambale Venkatesh 1 , Steven G. Lloyd 2 , Mustafa I. Ahmed 2 , Himanshu Gupta 2 ,
Louid Dell'Italia 2 , Thomas S. Denney Jr. 1
1 Electrical and Computer Engineering, Auburn University, Auburn, AL, United States; 2 University of Alabama
at Birmingham
Accurate assessment of right ventricular (RV) function is clinically important – particularly in patients with pulmonary hypertension
(PHTN). Compared to the left ventricle (LV), however, analysis of RV function is relatively difficult because of relatively thin walls
and lack of geometric symmetry. Also in PHTN, higher systolic blood pressure in the RV can cause excursion of the interventricular