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ELECTRONIC POSTER - ismrm

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15:00 4945. RF Concatenation with Spiral In-And-Out Trajectory for Two-Dimensional Large-<br />

Tip-Angle Excitation<br />

Seung-Kyun Lee 1 , Dan Xu 2 , W A. Grissom 3 , Ileana Hancu 1 , Mika W. Vogel 4<br />

1 GE Global Research, Niskayuna, NY, United States; 2 Applied Science Laboratory, GE Healthcare, Waukesha,<br />

WI; 3 Department of Electrical Engineering and Radiology, Stanford University, Stanford, CA; 4 GE Global<br />

Research, Munich, Bavaria, Germany<br />

We demonstrate that the time-reversed RF concatenation principle, which was previously considered in one-dimensional nonadiabatic<br />

inversion pulse design, can be extended to multi-dimensional and multi-coil excitation pulses. We present general analytical<br />

formulation of the concatenation principle, and demonstrate its use in (i) simulated inversion in 8-channel parallel transmit, and (ii) invivo<br />

inversion experiment on a single channel system with a human subject. The off-resonance field sensitivity, which is a drawback<br />

of the concatenation method in one dimension, is significantly reduced for two-dimensional excitation when a spiral in- and outtrajectory<br />

is employed.<br />

15:30 4946. Design of Velocity Selective Inversion Pulse for VSASL Using the Shinnar-Le Roux<br />

Algorithm<br />

Kangrong Zhu 1 , Kui Ying 1 , Xinlu Xu 1 , William Grissom 2 , Michael Lustig 2 , John Pauly 2<br />

1 Tsinghua University, Beijing, China; 2 Stanford University, Stanford, CA, United States<br />

A new method which employs the SLR algorithm to generate velocity selective inversion pulse is presented and a design example is<br />

shown. Simulation results demonstrate that the slice profile of the designed inversion pulse is very smooth and that the pulse has good<br />

resistance to B1 inhomogeneity. Phantom studies verified the frequency selectivity and the velocity selectivity of the pulse. All results<br />

imply that the pulse is potentially suitable for use as a tagging pulse in VSASL. The design method enables the pulse designer to<br />

explicitly trade off among important parameters such as slice thickness, pulse duration and pass-band ripple.<br />

Tuesday 13:30-15:30 Computer 116<br />

13:30 4947. Combined Excitation and Partial Saturation to Reduce Inflow Enhancement<br />

Misung Han 1,2 , Brian A. Hargreaves 1<br />

1 Radiology, Stanford University, Stanford, CA, United States; 2 Electrical Engineering, Stanford University,<br />

Stanford, CA, United States<br />

Partially saturating outer slab upstream can reduce inflow enhancement and pulsatile ghost artifacts by preparing flowing spins to a<br />

steady state before entering the imaging slab. However, adding another RF pulse and spoilers increases scan time. Here, we present a<br />

short RF pulse that simultaneously excites the imaging slab and partially saturates the outer slab. This pulse was designed and<br />

demonstrated by phantom and in vivo experiments for the RF-spoiled gradient echo sequence.<br />

14:00 4948. Partial Fourier Accelerated Selective Excitation Improves Pattern Fidelity at 9.4<br />

Tesla<br />

Kaveh Vahedipour 1 , Tony Stöcker 1 , N Jon Shah 1,2<br />

1 Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; 2 Department of<br />

Neurology, RWTH Aachen University, Aachen, Germany<br />

Partial Fourier Spatially has so far been only investigated in 1 dimension in form of asymmetric echoes. Recently, we have prposed to<br />

use partial Fourier excitations for higher dimension. This work encloses recent results and considerations.<br />

14:30 4949. T2-Weighted Spin Echo Pulse Sequence That Is Sensitive to Restricted Diffusion<br />

Ziqi Sun 1 , Robert Bartha 2<br />

1 The Ohio State University, Columbus, OH, United States; 2 Robarts Research Institute, London, Ontario,<br />

Canada<br />

A spin-echo (SE) pulse sequence incorporated with two selective adiabatic full passage (AFP) pulse trains separated by a time delay<br />

tau (varying with TE) and located symmetrically on both sides of an amplitude modulated 180 degree refocusing pulse. Apparent T2<br />

and diffusion measurements on a phantom of multi-medium and multi-compartment demonstrated that the customized SE sequence<br />

generated T2-weighted contrast that is specifically sensitive to restricted diffusion in the phantom media in comparison to those of the<br />

conventional SE and CPMG pulse sequences.<br />

15:00 4950. On the Generation of Half-Sinc Pulses for Optimal Excitation Profile<br />

Keith Wachowicz 1 , B. Gino Fallone 2,3<br />

1 Medical Physics, Cross Cancer Institute, Edmonton, Alberta, Canada; 2 Medical Physics, Cross Cancer<br />

Institute, Canada; 3 University of Alberta<br />

In this work, we perform simulations to explore the effects of fast T2 relaxation on excitation with half-sinc pulses. The generation of<br />

pulses for optimal excitation profiles is explored in terms of optimal flip angle, for which standard reasoning used for longer T2<br />

species will no longer hold. Also, the number of side lobes to generate an optimal excitation profile was investigated, since, unlike the<br />

case of longer T2, using more side-lobes does not necessarily result in a better profile.

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