ELECTRONIC POSTER - ismrm

healthy controls using empathy for pain task. Based on our finding that the FM group did not show activation in the several pain
empathy related areas during the empathy for pain task, the current study suggest that DLPFC and ACC hypoactivity in FM group is
associated with a deficit in cognitive function in empathizing and evaluating other’s pain.
14:00 3525. Interpersonal Relationships and Intimacy Affect Top-Down Processing of Empathy
I-Yun Chen 1 , Kun-Hsien Chou 2 , Chun-Wei Lan 3 , Ya-Wei Cheng 1 , Ching-Po Lin 1,3
1 Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan; 2 Institute of Biomedical
Engineering, National Yang-Ming University, Taipei, Taiwan; 3 Institute of Biomedical imaging and
Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
Being in a close relationship is essential to human life. Such closeness can be described as including other in the self. To what extent
does imagining a loved one differ from imagining an unfamiliar individual being in painful situations? In this functional MRI study,
participants were exposed to animated stimuli depicting hands or feet in painful and non-painful situations, and instructed to imagine
the scenarios perceived from three different perspectives: self, loved one and stranger. The results demonstrate that interpersonal
relationships and intimacy affect top-down processing of empathy, as indicated by greater overlap between neural representations of
self and other.
14:30 3526. Improved Methods and Analysis in FMRI Studies to Assess Taste and Aroma
Integration
Sally Eldeghaidy 1,2 , Luca Marciani 3 , Johann C. Pfeiffer 4 , Joanne Hort 4 , Kay Head 2 , Andy
J. Taylor 4 , Robin C. Spiller 3 , Penny A. Gowland 2 , Sue Francis 2
1 Physics Departement, Suez Canal University , Ismailia, Egypt; 2 Sir Peter Mansfield Magnetic Resonance
Centre, Nottingham, United Kingdom; 3 Nottingham Digestive Diseases Centre NIHR Biomedical Research
Unit,, Nottingham University Hospitals, Nottingham, United Kingdom; 4 Flavour Research Group, Division of
Food Sciences, University of Nottingham, Nottingham, United Kingdom
Improved paradigms (including dual-echo EPI, spray delivered samples and an immediate swallow) and subtraction and conjunction
analysis methods have been used to study the crossmodal, supra-additive response to a congruent flavour. We show the control
stimulus may cancel out some cortical responses of interest, and that a conjugate analysis is advantageous to subtraction analysis,
showing additional supra-additive activity in oral somatosensory areas (SII and inferior parietal areas). This supports the suggested
model for flavour perception that the oral somatomotor areas play a principal role in binding taste, aroma and oral somatosensory
modalities into the flavour percept.
15:00 3527. Representation of Sweet and Salty Taste Intensity in the Brain
Maartje Sara Spetter 1 , Paul A.M. Smeets 1 , Cornelis de Graaf 2 , Max A. Viergever 1
1 Radiology, Image Sciences Institute, Utrecht, Netherlands; 2 Human Nutrition, Wageningen University,
Wageningen , Netherlands
Sucrose and salt are commonly used to season foods. We investigated the brain representation of sweet and salty taste intensity using
fMRI. 14 subjects visited twice and tasted a range of four solutions of either sucrose or salt (0 – 1 M). Insula activation increased with
increasing concentration for both salt and sucrose. Moreover, despite similar subjective intensity ratings, insula activation by salt
increased more with concentration than that by sucrose. Amygdala activation increased with increasing salt concentration only. In
conclusion, sweet and salty taste intensity is represented in the insula.The greater responsiveness of the brain to saline provides
supports for the idea that sensory-specific satiety may be stronger for savoury than for sweet tastes.
Wednesday 13:30-15:30 Computer 26
13:30 3528. The Neural Correlates of Everyday Recognition Memory.
Abdelmalek Benattayallah 1 , Fraser Milton 2 , Nils Muhlert 3 , Chris Butler 4 , Adam Zeman
1 Peninsula Medical School, Exeter, Devon, United Kingdom; 2 Psychology, University of Exeter, Exeter, Devon,
United Kingdom; 3 Peninsula Medical School, University of Exeter, Exeter, Devon, United Kingdom;
4 University of Oxford
We used an automatic camera, SenseCam, to create a recognition memory test for real-life events. Using fMRI, participants classified
images as strongly or weakly remembered, strongly or weakly familiar or novel, 36 hours and 5-6 months after image acquisition. At
36 hours, diverse neocortical regions were activated by recollected and familiar stimuli. There was increasing activation in right
hippocampus/ posterior parahippocampal gyrus (pPHG) with increasing memory strength. Strong recollection elicited greater activity
in left posterior hippocampus/pPHG than weak recollection. At 5-6 months, MTL activated for familiarity but not recollection
memory. Neocortical regions were recruited for both recollection and familiarity processes.
14:00 3529. Altered Working Memory Process in Welders Using N-Back FMRI
Jeehye Seo 1 , Jae-jun Lee 1 , Hui-jin Song 1 , Joo-hyun Kim 1 , Kyung Jin Suh 2 , Sung Woo
Kim 2 , Young Hwan Lee 3 , Dong Soo Yoo 4 , Yongmin Chang 1,5
1 Medical & Biological Engineering, Kyungpook National University, Daegu, Korea, Republic of; 2 Radiology,
College of Medicine, Dongguk University, Gyungju; 3 Radiology, College of Medicine, Catholic University,
Daegu; 4 Radiology, College of Medicine, Dankook University, Chunan; 5 Diagnostic Radiology, Kyungpook
National University, Daegu, Korea, Republic of
Excessive accumulation of Mn in the globus pallidus(GP) is known to cause cognitive and motor deficits in human. Until now pallidal
index(PI) in terms of T1 bright signal intensity at GP is only imaging diagnostic measure to manganism. Currently no functional