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14:00 4555. Incidental Enhancing Lesions Found on Preoperative Breast MRI: Management<br />

and Role of Second Look Ultrasound<br />

Maria Laura Luciani 1 , Federica Pediconi, Valeria Dominelli, Marianna Telesca, Valeria<br />

Casali, Federica Vasselli, Carlo Catalano, Roberto Passariello<br />

1 of Radiological Sciences, "La Sapienza" University of Rome, Rome, Italy<br />

We evaluated the role of second look US for the study of occasional lesions detected on preoperative breast MRI and we proved it can<br />

be an helpful way to localize and study lesions depicted only on preoperative breast MRI.<br />

14:30 4556. Correlation of Prognostic Parameters and MR Perfusion Parameters in Dynamic<br />

Contrast Enhanced MRI (DCE-MRI) in Patients with Breast Cancers<br />

Nariya Cho 1 , In Chan Song 1 , Yong Sik Bang 1 , Woo Kyung Moon 1<br />

1 Department of Radiology, Seoul National University Hospital, Seoul, Korea, Republic of<br />

Transfer constant obtained from DCE-MRI are well correlated with tumor size and histologic grade of breast cancer, which shows its<br />

potential as a noninvasive prognostic parameter in the breast cancer patient.<br />

15:00 4557. The Evaluation of the Disease Extent in Patient with Ductal Carcinoma in Situ:<br />

Comparison of Mammography, Sonography, and MRI<br />

Kyoung Eun Lee 1 , Hak Hee Kim 1 , Jeong-Hee Sohn 1 , Hee Jung Shin 1 , Gyungyub Gong 2 ,<br />

Se Hyun Ahn 3 , Hyeon Sook Kim 4 , Eun Suk Cha 4<br />

1 Radiology, Asan Medical Center, Seoul, Korea, Republic of; 2 Pathology, Asan Medical Center, Seoul, Korea,<br />

Republic of; 3 General Surgery, Asan Medical Center, Seoul, Korea, Republic of; 4 Radiology, The Catholic<br />

University of Korea, Seoul, Korea, Republic of<br />

We think that in patient with DCIS, complemented MRI may be best establish the presence and extent of disease.<br />

Wednesday 13:30-15:30 Computer 91<br />

13:30 4558. Multifunctional MRI to Detect and Localize Multifocal and Multicentric Breast<br />

Cancer<br />

Elizabeth O'Flynn 1 , Anna Kirby 2 , Maria Schmidt 1 , Ashutosh Nerurkar 3 , Veronica A.<br />

Morgan 1 , Erica Scurr 1 , John Yarnold 2 , Nandita M. deSouza 1<br />

1 Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research & Royal Marsden NHS<br />

Foundation Trust, Sutton, Surrey, United Kingdom; 2 Clinical Academic Radiotherapy, Institute of Cancer<br />

Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; 3 Histopathology, Institute<br />

of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom<br />

This pilot study demonstrates the accuracy of dynamic contrast-enhanced (DCE)-MRI and diffusion-weighted (DW)-MRI in detecting<br />

and localising multifocal and multicentric disease in patients with breast cancer by correlating imaging with histopathology findings at<br />

mastectomy. DCE-MRI alone was most accurate in detecting satellite lesions (sensitivity of 89%), DW-MRI was least accurate<br />

(sensitivity 55%). Satellite lesions were found up to 22 mm from the edge of the index lesion. Accurate identification of satellite<br />

lesions with multifunctional MRI offers potential for monitoring the effects of local therapies on multifocal and multicentric disease,<br />

and in defining the target volume for partial breast irradiation.<br />

14:00 4559. Magnetic Resonance Imaging for Axillary Staging in Breast Cancer Patients<br />

Receiving Neoadjuvant Chemotherapy: Comparison with Ultrasonography and Positron<br />

Emission Tomography<br />

Sun Mi Kim 1 , Chae Yeon Lyou 1 , Mijung Jang 1<br />

1 Seoul National University Bundang Hospital, Seongnam-Si, Gyunggido, Korea, Republic of<br />

The presence of axillary lymph node(LN) metastases in breast cancer is an important factor in assessing prognosis and determines<br />

management. Although surgical biopsy remains the gold standard for the diagnosis of axillary LN metastasis but standard for surgical<br />

biopsy in monitoring for chemotherapy response does not established yet. Comprehensive and sequential staging of axilla using<br />

noninvasive diagnostic modalities has been approached and which would represent an importance advance in the management of<br />

breast cancer patients. This presentation evaluate the accuracy of comprehensive pre- and post-neoadjuvant chemotheraphy axillary<br />

staging via MRI, ultrasound imaging and positron emission tomography.<br />

14:30 4560. MRI Findings of Triple Negative Breast Cancer: A Comparison with Non Triple<br />

Negative Breast Cancer<br />

Jae Jeong Choi 1 , Sung Hun Kim 2 , Eun Suk Cha 3 , Hyun Suk Kim 4 , Jae Young Byun 2 , Bong<br />

Joo Kang 2 , Ji Hye Lee 2<br />

1 Radiology, Seoul St. Mary's Hospital, Catholic University of Korea , Seoul, Korea, Republic of; 2 Radiology,<br />

Seoul St. Mary's Hospital, Catholic University of Korea, Seoul, Korea, Republic of; 3 Radiology, St. Vincent's<br />

Hospital, Catholic University of Korea, Seoul, Korea, Republic of; 4 Radiology, St. Paul's Hospital, Catholic<br />

University of Korea, Seoul, Korea, Republic of<br />

We would like to submit our report titled ¡°MRI Findings of Triple Negative Breast Cancer: A Comparison with Non Triple Negative<br />

Breast Cancer¡¯¡¯. Triple negative breast cancer is a subtype with aggressive clinical behavior which currently lacks effective targeted

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