ELECTRONIC POSTER - ismrm

14:00 4715. Diffusion Weighted Imaging in Differentiating Malignant from Benign Intraductal
Papillary-Mucinous Neoplasm of the Pancreas
Atsushi Nakamoto 1 , Tonsok Kim 1 , Masatoshi Hori 1 , Hiromitsu Onishi 1 , Takahiro
Tsuboyama 1 , Mitsuaki Tatsumi 1 , Noboru Maeda 1 , Hiroki Higashihara 1 , Keigo Osuga 1 ,
Kaname Tomoda 1
1 Department of Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
We retrospectively evaluated the diagnostic performance of diffusion-weighted imaging (DWI) and apparent diffusion coefficient
(ADC) value for differentiating malignant intraductal papillary-mucinous neoplasm (IPMN) of the pancreas from benign IPMN. The
mean minimum ADC value of malignant IPMN was lower than that of benign IPMN (P < 0.001). Mean Az value, sensitivity,
specificity and accuracy of MR imaging with DWI were higher than those of MR imaging without DWI, although differences were
not significant. We conclude that DWI and measurement of minimum ADC value would be helpful for differentiating malignant
IPMN form benign IPMN.
14:30 4716. New Application Screening for Malignant Tumors Using the Lesion to Spinal Cord
Ratio (LSR) in Diffusion Weighted Images
Mamoru Takahashi 1 , Yasuo Takehara 2 , Takahiro Natsume 3 , Norihiro Tooyama,
Katsutoshi Ichijo, Harumi Sakahara 2 , Atsushi Nozaki 4
1 Seirei Mikatabara General Hospital, Hamamatsu, Shizuoka, Japan; 2 Hamamatsu University of Medicine;
3 Seirei Hamamatsu General Hospital; 4 GE Healthcare Japan
Problem: Tumor detection based on apparent diffusion co-efficient (ADC) is not always efficient and accurate on the high b-value
diffusion weighted image (DWI). Method: The signal intensity ratio between lesions and spinal cord signal (LSR) were measured on
DWI. The LSR was higher in malignant tumors than in other lesions. Tumor screening application gLSR maph was developed
based on the signal intensity ratio between the lesions and the spinal cord signal on DWI. Results: With the cut-off of 0.45 for LSR,
sensitivity for malignant tumor was 100%. Using the color map, effective and robust tumor screening was feasible on DWI.
15:00 4717. Nodal Volumetric Histographic ADC Changes Associated with Successful
Chemotherapy of Adolescent and Childhood Lymphoma
Shonit Punwani 1 , Alan Bainbridge 1 , Stuart Taylor 1 , Steven Daw 2 , Ananth Shankar 2 , Paul
Humphries 1
1 Radiology, University College London Hospital, London, United Kingdom; 2 Paediatrics, University College
London Hospital, London, United Kingdom
Cellular density should decrease following successful chemotherapy of lymphomatous tissue and a corresponding rise of ADC is
expected. This study investigates the extent and nature of histographic post treatment ADC changes associated with a successful
treatment outcome in childhood and adolescent patients with lymphoma.
Wednesday 13:30-15:30 Computer 101
13:30 4718. Distortion Correction of Body Diffusion Weighted Images Using Three Point-Dixon
Method
Saori Mori 1 , Isao Muro 1 , Hisamoto Moriguchi 1 , Tomohiko Horie 1 , Masatoshi Honda 1 ,
Tesuo Ogino 2 , Makoto Obara 2 , Yutaka Imai 1
1 Radiology, Tokai university, Isehara, Kanagawa, Japan; 2 Philips Healthcare Asia Pacific, Shinagawa, Tokyo,
Japan
Significant distortion can often be observed in body diffusion weighted images using single shot EPI. In this study, we demonstrate
that a B0 map obtained using three point-Dixon method is useful to correct for distortion. The correlation coefficients of corrected
images were increased by 0.02 or greater from those of the uncorrected images. In this method, although prescan is required, it
requires about a minute and a B0 map obtained from the prescan can be applied to 50 images. This method is quite useful in practice
since a B0 map created using this method enables good distortion correction.
14:00 4719. Motion Induced Signal Non-Uniformity Correction with Asymmetric Bipolar MPG
on Liver DWI
Tetsuo Ogino 1 , Tomohiko Horie 2 , Isao Muro 2 , Marc Van Cauteren 3 , taro takahara 4
1 Clinical Science , Philips Electronics Japan, LTD, Minato-ku, Tokyo, Japan; 2 Tokai Univ. Hospital, Japan;
3 Philips Healthcare Asia Pacific, minato-ku, Tokyo, Japan; 4 Division of Radiology, Radiotherapy and Nuclear
Medicine (RRN), University Medical Center (UMC) Utrecht, Utrecht, Netherlands
Respiratory and Cardiac motion affects DWI IQ on liver. A voxel deformation due to motion under Motion Probing Gradient(MPG)
induces spin phase dispersion in a voxel and results signal loss. By replacing conventional MPG with a pair of bipolar gradient, the
signal loss is reduced significantly. However, minimum TE and TR are prolonged due to low efficiency of such type of MPG. We
propose a novel MPG method which is formed as hybrid of conventional MPG and bipolar MPG. Image quality of liver diffusion is
significantly improved with slight scan time prolongation from conventional respiratory triggered DWI.