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ELECTRONIC POSTER - ismrm

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Tuesday 13:30-15:30 Computer 83<br />

13:30 4426. 3D MRA with Dynamic Sequence Switching: Improved Imaging of the Arterial and<br />

Venous Phases<br />

Petrice M. Mostardi 1 , Clifton R. Haider 1 , Norbert G. Campeau 1 , Stephen J. Riederer 1<br />

1 Radiology, Mayo Clinic, Rochester, MN, United States<br />

Time-resolved CE-MRA is widely used for imaging the intracranial arterial system, while a single high spatial resolution acquisition<br />

is generally used for the intracranial venous system. The goal of this work was to combine these two studies into a single contrastenhanced<br />

acquisition. A time-resolved CAPR sequence was played out for about 50 sec for arterial phase imaging, providing images<br />

every 3.57 sec. Then, by seamlessly switching to a high spatial resolution, 38 sec long scan, data for a venogram was acquired. High<br />

speed reconstruction further allows the time of switching to be done in real time on a patient-specific basis.<br />

14:00 4427. High-Resolution Non-Contrast Enhanced Dark Blood Brain Vessel Imaging Using a<br />

Balanced Steady State 3D Projection Reconstruction Sequence<br />

Aiming Lu 1 , Keith R. Thulborn 1<br />

1 Center for MR Research, University of Illinois at Chicago, Chicago, IL, United States<br />

Balanced steady-state free precession (SSFP) sequences have been used for non-contrast enhanced vessel imaging due to its high SNR<br />

efficiency and bright blood signal. However, as cerebrospinal fluid (CSF) signal is also bright in SSFP images, the application of these<br />

techniques to brain has been limited. In this work, we demonstrate that instead of appearing as bright signal, the vessels in the brain<br />

have low signal intensity in high-resolution 3T images. Using a dual-half-echo 3D projection reconstruction based SSFP sequence, our<br />

results show that non-contrast enhanced high-resolution vessel imaging can be obtained rapidly along with high quality T2-contrast<br />

images.<br />

14:30 4428. Automated Calculation of Wall Shear Stress in the Middle Cerebral Arteries of<br />

Healthy Volunteers Using PC-VIPR and Spline Interpolation<br />

Warren Chang 1 , Yijing Wu, Kevin Johnson, Andrew Wentland 2 , Steven Kecskemeti 3 ,<br />

Charles Mistretta 1 , Patrick Turski 1<br />

1 Radiology/Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI,<br />

United States; 2 Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison , WI,<br />

United States; 3 Physics/Medical Physics, University of Wisconsin School of Medicine and Public Health,<br />

Madison, WI, United States<br />

Time-average wall shear stress in the M1 segment of the middle cerebral arteries of 10 healthy volunteers was calculated using<br />

automated spline interpolation. The velocity measurements were acquired using PC-VIPR, a fast undersampled phase-contrast MRA<br />

technique that allows whole-brain imaging in 5 minutes with sub-millimeter spatial resolution. The calculated average WSS for the<br />

proximal MCA was 0.20 Pa (S.D. 0.016 Pa) consistent with published values for PC-MRA. This report shows that fast, automated,<br />

non-invasive estimation of wall shear stress can be obtained in middle and large-sized intracranial arteries that are prone to the<br />

development of atherosclerosis and other cerebrovascular disorders.<br />

15:00 4429. Low Dose, Supraortic 3D Time-Resolved MR Angiography at 3T: Comparison with<br />

High Spatial Resolution 3D Contrast-Enhanced MR Angiography<br />

Yoon-joo Lee 1 , Jae-young Byun 1 , So-lyung Jung 1 , Won-jong Yoo 1 , Young-joo Kim 1 , Kookjin<br />

Ahn 1 , Bum-soo KIM 1<br />

1 Department of Radiology, The Catholic University of Korea, Seoul, Korea, Republic of<br />

This study evaluates feasibility and effectiveness of low-dose TR-CEMRA (with injection of 1cc of Gadobutrol followed by 20cc of<br />

saline) performed in the assessment of supraaortic vessel, acquired with combination of parallel imaging (GRAPA) and view-sharing<br />

technique (TWIST) at 3T. Retrospective evaluation of image quality and stenosis grade by two neuroradiologist was done, and<br />

compared with the results from high-resolution single-phase CEMRA. The overall image quality for low-dose TR-CEMRA was in<br />

diagnostic range, comparable to HR-CEMRA. In grading of stenosis, TR-CEMRA showed concordant results with HR-CEMRA in<br />

90.8%, with relatively more number of overestimation than underestimation.<br />

Wednesday 13:30-15:30 Computer 83<br />

13:30 4430. Non-Contrast Dynamic MRA Using TrueFISP Based Spin Tagging with Alternating<br />

Radiofrequency (TrueSTAR) in Cerebral Arteriovenous Malformation<br />

Sumei Wang 1 , Lirong Yan 2 , Yan Zhuo 2 , Ronald L. Wolf 1 , Michael F. Stiefel 1 , Jing An 3 ,<br />

Elias R. Melhem 1 , Jiongjiong Wang 1<br />

1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 State Key Laboratory of Brain and<br />

Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China; 3 Siemens Mindit<br />

Magnetic Resonance Ltd., Shenzhen, China<br />

Five patients with arteriovenous malformations (AVMs) were evaluated using a novel dynamic MRA (dMRA) technique termed<br />

TrueFISP based Spin Tagging with Alternating Radiofrequency (TrueSTAR). The results are compatible with time-of-flight (TOF)<br />

MRA results. Dynamic MRA demonstrated the blood flow pattern through feeding arteries, nidus and draining veins with high<br />

temporal resolution (

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