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ELECTRONIC POSTER - ismrm

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15:00 4894. Faster Acquisition of MR Images with Double Quantum Filtering by Regularization<br />

Genevieve Guillot 1 , Yongchao Xu 1 , Slawomir Kusmia 1 , Hadia Hanachi 1 , Jean-François<br />

Giovannelli 2 , Alain Herment 3<br />

1 U2R2M UMR8081 CNRS, Orsay, France, France; 2 LAPS / IMS UMR5218, Bordeaux, France, France; 3 3-<br />

LIF U678 INSERM / UMR-S UPMC, Paris, France, France<br />

MRI with Double Quantum Filter (DQF) gives a direct access to water linked to macromolecules, but requires 16 up to 64 repetitions<br />

of the acquisition scheme with different phases of the RF pulses in the DQ filter to select the DQ signal. We reduced the number of<br />

phase encoding lines kept in the data for each DQF step, employing a regularization method to compute each image. The acquisition<br />

time could be reduced by 2/3 without any significant loss of contrast and minor loss of contrast on contours. Even faster acquisition<br />

should be possible with radial or spiral k-space trajectories.<br />

Topics in Parallel Imaging<br />

Hall B Monday 14:00-16:00 Computer 113<br />

14:00 4895. Noise-Facilitated GRAPPA Reconstruction for FMRI<br />

Hu Cheng 1 , Wei Lin 2 , Feng Huang 2<br />

1 Indiana University, Bloomington, IN, United States; 2 Invivo Diagnostic Imaging, Gainesville, FL, United<br />

States<br />

In fMRI, temporal SNR is the main concern in the optimization of parallel imaging algorithms such as GRAPPA. It is shown in this<br />

work that adding noise to the auto-calibration signal (ACS) region of GRAPPA data can increase the temporal SNR of fMRI series,<br />

with a minimal impact on image quality. Simulation on the EPI images of a phantom and human subject demonstrated that image<br />

quality can be improved by adding a certain amount of noise to the raw data of reference scans, while the temporal SNR can be further<br />

improved with a higher level of additive ACS noise.<br />

14:30 4896. Undersampled Multi Coil Image Reconstruction for Fast FMRI Using Adaptive<br />

Linear Neurons<br />

Thimo Grotz 1 , Benjamin Zahneisen 1 , Marco Reisert 1 , Maxim Zaitsev 1 , Jürgen Hennig 1<br />

1 Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany<br />

Standard fMRI experiments have a rather limited temporal resolution of 1-3s. The temporal resolution of fMRI experiments can be<br />

increased by an order of magnitude by acquiring less k-space and using a high number of receive channels. Image reconstruction is<br />

thus an ill-posed inverse problem. Here we would like to introduce a new approach, based on neural networks, to reconstruct the<br />

undersampled fMRI data that offers a significantly improved point spread function with reduced spatial spread and hence improved<br />

spatial localization of activation.<br />

15:00 4897. Time Dependent Regularization for Functional Magnetic Resonance Inverse<br />

Imaging<br />

Aapo Nummenmaa 1,2 , Matti S. Hamalainen 1 , Fa-Hsuan Lin 1,3<br />

1 MGH-MIT-HMS Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States;<br />

2 Department of Biomedical Engineering and Computational Science, Helsinki University of Technology,<br />

Espoo, Finland; 3 Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan<br />

We propose a novel method for time dependent regularization of functional magnetic resonance Inverse Imaging (InI). A Variational<br />

Bayesian approximation with a dynamic model for the regularization is constructed to obtain an automatic, temporally adaptive<br />

estimation algorithm. The proposed method is compared with the standard Minimum-Norm Estimate (MNE) by using simulated InI<br />

data. The dynamic dMNE shows significant improvements in determining the activation onset from the baseline period.<br />

15:30 4898. Magnetic Resonance Multi-View Inverse Imaging (MV InI) for Human Brain<br />

Kevin Wen-Kai Tsai 1 , Thomas Witzel 2 , Fa-Hsuan Lin 1,3<br />

1 Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; 2 A. A. Martinos Center; 3 A.<br />

A. Martinos Center, Massachusetts General Hospital, Charlestown, MA, United States<br />

To solve the anisotropic spatial resolution of MR inverse imaging (InI) reconstruction method, we propose the multi-view InI (MV<br />

InI) to using a few projections and a highly parallel detection to achieve high spatiotemporal MR dynamic imaging. Specifically, we<br />

used three orthogonal projections and a 32-channel head coil array to achieve the effective TR of 300 ms and 4 mm3 isotropic spatial<br />

resolution. We demonstrated the acquisitions and reconstruction of MV InI using in vivo data. This method achieved a 8 times faster<br />

temporal resolution than conventional multi-slice EPI acquisitions.<br />

Tuesday 13:30-15:30 Computer 113<br />

13:30 4899. Homotopic l 0 Minimization Technique Applied to Dynamic Cardiac MR Imaging<br />

Muhammad Usman 1 , Philip G. Batchelor 1<br />

1 King's College London, London, United Kingdom<br />

The L1 minimization technique has been empirically demonstrated to exactly recover an S-sparse signal with about 3S-5S<br />

measurements. In order to get exact reconstruction with smaller number of measurements, recently, for static images, Trzasko has

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