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ELECTRONIC POSTER - ismrm

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Laboratory, GE Healthcare, Tokyo, Japan; 4 Applied Science Laboratory, GE Healthcare, Waukesha, WI, United<br />

States<br />

This work presents validation of an inflow-enhanced, inversion-recovery (IR) balanced steady state free precession (bSSFP) based<br />

non-contrast-enhanced MRA (NCE-MRA) for assessment of renal arteries at 3T in patients with suspected renal artery stenosis or<br />

with a history of renal artery transplant. NCE-MRA with inflow-enhanced IR bSSFP produced consistent results and demonstrated<br />

moderate agreement with CE-MRA for both readers and strong inter-observer agreement for grading renal artery stenosis >50%.<br />

Thursday 13:30-15:30 Computer 41<br />

13:30 3769. Time-SLIP Versus DSA in Patients with Renal Artery Stenosis<br />

Isabelle Parienty 1 , Faiza Admiraal-Behloul 2 , Francis Jouniaux 1 , Michel Piotin 3 , Guy<br />

Rostoker 3<br />

1 Centre d'Imagerie du Bois de Verrière, Antony, France; 2 MRI, Toshiba Medical Systems Europe, Zoetermeer,<br />

Netherlands; 3 Nephrology, Centre Hospitalier Claude Galien, Paris, France<br />

The purpose of this study was to compare the findings in non-contrast enhanced MRA using the Time Spatial Labeling Inversion<br />

Pulse (Time-SLIP) technique to those of Digital Subtraction Angiography (DSA) in patients with significant renal artery stenosis<br />

(>60%, or >50% with post stenotic dilation).<br />

14:00 3770. Respiratory Rate Regulation for Optimal Time-SLIP Imaging of Renal Arteries<br />

Francis Jouniaux 1 , Isabelle Parienty 1 , Faiza Admiraal-Behloul 2<br />

1 Centre d'Imagerie du Bois de Verrière, Antony, France; 2 MRI, Toshiba Medical Systems Europe, Zoetermeer,<br />

Netherlands<br />

Respiratory gated non contrast enhanced MR angiography using Time-Spatial inversion labeling pulse (Time-SLIP) is a well<br />

established technique at our institution for the exploration of renal arteries. Since 2007, we scanned more than 450 patients with age<br />

ranging for 18 to 92 year old. Patients with fast and/or irregular respiration rates (RR) can be very challenging to image. Most of the<br />

difficult patients are old (80+), or have a cardiac disease and/or a respiratory disease. A breath hold of more than 16s is intolerable for<br />

most of these patients. We describe how regulating the respiratory rate can significantly improve the image quality and the success<br />

rate of Time-SLIP.<br />

14:30 3771. Assessment of Non-Contrast Angiography in Diabetic Patients<br />

Erin Jane Kelly 1 , JoEllyn L. L. Stolinski 2 , James Jelinek 2<br />

1 Magnetic Resonance, Toshiba America Medical Systems, Tustin, CA, United States; 2 Radiology, Washington<br />

Hospital Center, Washington, D.C., United States<br />

Diabetes is highly associated with renal failure and peripheral artery disease. In light of the association between MRI contrast media<br />

and the onset of NSF/NSD, it is increasingly important to replace CE-MRA with non-contrast angiographic imaging techniques, such<br />

as Fresh Blood Imaging and Time-SLIP. In this study, diabetic patients referred for and MRA were imaged with FBI and Time-SLIP<br />

for peripheral run-offs and renal angiography. Image Quality and Diagnostic Confidence scores indicate that FBI and Time-SLIP are<br />

both safe and effective alternatives to CE-MRA in this patient group.<br />

15:00 3772. An MRI Examination for Evaluation of Aortic Dissection Using a Blood Pool Agent<br />

Rachel Clough 1 , Tarique Hussain 1 , Sergio Uribe 1 , Peter Taylor 2 , Reza Razavi 1 , Tobias<br />

Schaeffter 1 , Matthew Waltham 2<br />

1 Division of Imaging Sciences, King's College London, London, United Kingdom; 2 Guy’s and St Thomas’ NHS<br />

Foundation Trust, St Thomas' Hospital, London, United Kingdom<br />

An MRI examination for evaluation of aortic dissection using a blood-pool agent is presented. The aims of this study were to<br />

investigate the use of direct thrombus MRI and quantitative flow analysis for the determination of false lumen thrombus volumes in<br />

patients with Type B aortic dissection. It is shown that blood-pool imaging together with direct thrombus MRI allows assessment of<br />

aortic anatomy and more accurate quantification of false lumen thrombosis compared with CT. Current clinical trials using false<br />

lumen thrombosis as a primary endpoint should consider multi-parametric MRI as the preferred diagnostic tool.<br />

MRA: Preclinical Technical Developments<br />

Hall B Monday 14:00-16:00 Computer 42<br />

14:00 3773. Magnetic Resonance Venography with a Blood Pool Contrast Medium<br />

Teik Choon See 1 , Andrew Winterbottom 1 , Edmund Soh 2 , Ilse Joubert 1 , Martin Graves 1 ,<br />

David Lomas 1<br />

1 Radiology, University of Cambridge and Addenbrooke's Hospital, Cambridge, Cambridgeshire, United<br />

Kingdom; 2 Singapore General Hospital, Singapore<br />

Our prospective clinical trial authorised study aims to assess MR venography of the neck and thoracic central veinous system using<br />

Vasovist® (gadofosveset trisodium, Schering), a blood pool contrast agent, for first pass (FP) and steady state (SS) imaging. Images<br />

are assessed independently for image quality, artefacts, stenosis, and thrombosis. Sixteen participants recruited to date and 144 venous<br />

segments assessed. The result shows very favourable SS imaging quality compared to FP (although not quite statistically significant)

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