ELECTRONIC POSTER - ismrm

transmural thickening and circumferential shortening. Characterization of the remote, border zone and infarct 3D strain is paramount
in understanding infarct expansion and in the development of therapies to mitigate remodeling.
14:30 3606. Cardiac Valve Position Prediction in CINE-BSSFP Images Using SURF
Hendrikus Joseph Alphons Crooijmans 1 , Philippe C. Cattin 2 , Oliver M. Weber 1,3 , Klaus
Scheffler 1
1 Division of Radiological Physics, Department of Medical Radiology, University of Basel Hospital, Basel,
Switzerland; 2 Medical Image Analysis Center (MIAC), University of Basel, Basel, Switzerland; 3 Siemens
Healthcare, Zürich, Switzerland
The interest point detector and region descriptor SURF finds features in every image/phase of a series of CINE-bSSFP images. By the
help of user input, the best feature is selected in a Matlab program and corresponding features are automatically detected. If no feature
is found within preset limits, it is created by linear interpolation. User indicated points of interest are described as a function of the
position and diameter of the feature (all in the first image/phase), and can therefore be repositioned based on the corresponding
features in the succeeding images/phases. This method provides reliable fast online valve position detection.
15:00 3607. Comparison of Left Function Assessment Using Phonocardiogram and
Electrocardiogram Triggered 2D SSFP CINE MR Imaging at 1.5 T and 3.0 T
Tobias Frauenrath 1 , Meike Becker 2,3 , Fabian Hezel 1 , Gabriele A. Krombach 2 , Ute
Kremer 2 , Jeanette Schulz-Menger 1,3 , Thoralf Niendorf 1,3
1 Berlin Ultrahigh Field Facility, Max-Delbrueck Center for Molecular Medicine, 13125 Berlin, Germany;
2 Department of Radiology, University Hospital, RWTH, 52074 Aachen, Germany; 3 Experimental and Clinical
Research Center (ECRC), Charité Campus Buch, Humboldt-University, 13125 Berlin, Germany
As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to distortions and mistriggering increases and
with it the motivation for a cardiac triggering alternative. Hence, this study explores the suitability of acoustic cardiac triggering
(ACT) for left ventricular (LV) function assessment in healthy subjects at 1.5T and 3.0T.
Wednesday 13:30-15:30 Computer 31
13:30 3608. Improved Myocardial Mechanics as Assessed by MRI Generated Pressure-Volume
Loops Following AAV6-Mediated βARKct Gene Delivery.
James J. Pilla 1 , Jabaris D. Swain, Michael G. Katz, Anthony Fargnoli, Marina
Sumaroka, Catherine Tomasulo, Mihail Petrov, Rose Nolen-Walston, JanLee Jensen,
Hansell Stedman, Walter J. Koch 2 , Joseph Rabinowitz 2 , Charles R. Bridges
1 University of Pennsylvania, Philadelphia, PA, United States; 2 Thomas Jefferson University
Genetic modulation of ventricular function and remodeling may offer a novel therapeutic strategy for patients with acute ischemic left
ventricular (LV) dysfunction. We hypothesize that âARKct gene therapy will amplify the cardiac response to a beta-adrenergic agonist
resulting in improved function and efficiency as measured by MRI. MRI generated PV loops demonstrated that âARKct expression
improves global LV systolic performance and efficiency relative to controls. These results in a normal ovine subject, using a novel,
cardiac-specific gene delivery platform (MCARDTM) are predictive of long term efficacy in a clinically relevant large animal HF
model.
14:00 3609. Comparison of Magnetic Resonance Imaging and Doppler Echocardiography for
the Evaluation of Diastolic Function in Patients with Hypertrophic Cardiomyopathy
Yeon Hyeon Choe 1 , Eun Young Kim 2
1 Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic
of; 2 Radiology, Samsung Medical Center, Seoul, Korea, Republic of
Diastolic function parameters (mitral inflow velocities, deceleration time, E/A ratio) using phase contrast MRI showed good
correlation with that of echocardiography in patients with hypertrophic cardiomyopathy. Analysis of pulmonary vein flow velocity
was feasible on MRI and give additional information on diastolic function analysis.
14:30 3610. Evaluation of Patients with Systemic Sclerosis Prior to Hematopoietic Stem-Cell
Transplantation Using Cardiac Magnetic Resonance Imaging
Amir H. Davarpanah 1 , Aya Kino 1 , Kirsi Taimen 1 , Philip Hodnet 1 , Cormac Farrelly 1 ,
Jeremy Collins 1 , Sanjiv Shah 2 , Karin Dill 1 , Richard Burt 3 , James Carr 1
1 Department of Radiology, Cardiovascular Imaging, Northwestern University, chicago, IL, United States;
2 Department of Cardiology, Northwestern University, chicago, IL, United States; 3 Department of
Immunotherapy, Northwestern University, chicago, IL, United States
Using time to peak systole (TPS) from volumetric assessment of right ventricle, may have an important role in detecting both the
presence and severity of pulmonary hypertension (PH); It may apply to patients with systemic sclerosis overall, in whom early
detection of PH is of significant clinical importance.