ELECTRONIC POSTER - ismrm

15:00 4565. Isotropic 3D T2-Weighted MR Imaging for Female Pelvis with 3 Tesla MRI:
Feasibility Study
Junko Takahama 1 , Satoru Kitano 1 , Aki Takahashi 1 , Nagaaki Marugami 1 , Megumi
Takewa 1 , Takahiro Itoh 1 , Toshiaki Taoka 1 , Kimihiko Kichikawa 1
1 Radiology, Nara Medical University, Kashihara, Nara, Japan
The aim of this study was to compare the quality of images obtained with 3D T2-weighted sequence with the quality of conventional
2D T2-weighted images on 3.0-T MRI. Thirty consecutively registered patients were reviewed and analyzed quantitative measures of
contrast and image quality. Three-dimensional volumetric T2-weighted images on 3.0T MRI are of content quality and give better
anatomical recognition than conventional 2D images and have the added advantage of multiplanar and postprocessing capabilities.
MR Upper Abdomen I
Hall B Monday 14:00-16:00 Computer 92
14:00 4566. Semi-Quantitative Analysis of Normal Pancreas and Pancreatic Carcinoma with
Dynamic Contrast-Enhanced MR Imaging on a 3.0T System
Xiao Hong Ma 1 , Chun Wu Zhou 1 , Fei Sun 2 , Xin Ming Zhao 1 , Han Ouyang 1 , Hong Mei
Zhang 1
1 Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical
College, Beijing, China; 2 Shanghai Guided Medical Scientific Co. Ltd., Shanghai, China
Our study target to semi-quantify the perfusion parameters of normal pancreas and pancreatic carcinoma with three-dimension (3D)
high spatial and time resolution dynamic contrast enhanced (DCE) MRI on a 3.0T MR system. 31 patients who need abdomen contrast
enhancement scan but with normal pancreas and 34 pancreatic carcinoma patients underwent DCE-MRI on a 3.0T MR system with 8-
channel body coil. The perfusion parameters were measure including signal enhancement ratio at 30 seconds and 90 seconds after
injection (SER30, SER90), positive enhancement integral (PEI), time to peak (TTP) and maximum slope of increase (MSI). There is
no regional perfusion difference between the head, body and tail of normal pancreas, while there is significant difference between
lesion and non-lesion area of pancreatic carcinoma, and between normal pancreas and non-lesion area of pancreatic carcinoma.
14:30 4567. Effects of Oxygen Inhalation on T1 Relaxation Times in Abdominal Solid Organ
Kyung Ah Kim 1 , Mi-Suk Park 1 , Eun Ju Kim 2 , Myeong-Jin Kim 1 , Jin-Young Choi 1 , Hye-
Suk Hong 1 , Ki Whang Kim 1
1 Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of; 2 Clinical
science, MR, Philips Healthcare, Seoul, Korea, Republic of
We investigated the effect of the oxygen inhalation on relaxation times of T1 in abdominal solid organs, including liver, pancreas,
spleen, and kidney. The inhalation of oxygen caused T1 shortening in the pancreas, kidney and spleen, which have predominant
arterial blood supply, whereas no significant effect was noted in the liver, which has predominant portal venous blood supply. Our
results indicate that MRI is feasible to detect changes with oxygen inhalation, which differs considerably among organs, in a
noninvasive fashion. As a clinical application, the effect of oxygen on various normal and pathologic tissues may be used as a
biomarker of arterial flow, oxygen delivery to organs, and hypoxic status.
15:00 4568. Aged Vs. Fresh Blood for the Treatment of Hemorrhagic Shock; Differential Effect
on Liver Outcome and Possible Mechanism
Idit Matot 1 , Miriam Katz 2 , Orit Pappo 3 , Nathalie Corchia 4 , Gregory Barshtein 5 , Shaul
Yedgar 5 , Rinat Abramovitch, 6
1 Department of Anesthesiology & Intensive Care, Tel Aviv, Sourasky Medical Center, Tel Aviv, Israel;
2 Department of Anesthesiology, Rabin Medical Center, Petach Tiqva, Israel; 3 Pathology, Hadassah Hebrew
University Medical Center, Jerusalem, Israel; 4 he Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew
University Medical Center, Jerusalem, Israel; 5 Department of Biochemistry, Hebrew University, Jerusalem,
Israel; 6 MRI/MRS lab HBRC, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Concerns have recently been raised about the safety of transfusing stored-blood. Several studies have suggested that the risk of
complications increases when transfused blood has been stored for long period. The liver is a target for injury in low flow states
associated with trauma and hemorrhage. We studied the effect of blood resuscitation (fresh vs. Stored-blood) on liver injury. In rats,
transfusion of blood stored longer than 4 days increased liver injury. This was associated with significant changes in the viscoelastic
characteristics of the stored-blood and unrelated to the oxygen-carrying-capacity, cytokines in the stored-blood or the RBC/endothelial
cells adherence properties.