TABLE OF CONTENTS - BGB Analytik AG

ZORBAX Solvent Saver
• Provide 60% reduction in mobile phase usage and waste generation compared to
a 4.6 mm ID column
• Provide 2- to 3-fold signal-to-noise (S/N ratio) improvement
• Deliver optimal LC/MS performance at intermediate flow rates
• Can be used with most conventional LC instrument configurations without modification
• Solvent Saver columns are available in 1.8, 3.5 and 5 µm particle sizes
Agilent ZORBAX Solvent Saver columns have a 3.0 mm internal diameter. This is ideal for
reducing solvent usage by 50% over 4.6 mm ID columns. Solvent Saver columns are also
ideal for LC/MS. With a typical flow rate of 0.5 ml/min, these columns are compatible with
almost all LC interfaces. These columns also improve sensitivity 2 to 3 times over 4.6 mm ID
columns. Solvent Saver columns can be used with conventional HPLC instruments and are a
good choice for cost effective analyses.
Solvent Saver Columns Provide up to 60% Reduction
in Solvent Use and Waste
Column A: ZORBAX SB-C18
883975-902
4.6 x 150 mm, 5 µm
Column B: ZORBAX SB-C18
883975-302
3.0 x 150 mm, 5 µm
Mobile Phase: 20% ACN: 80% 0.2 M Na2HPO4
+ 0.1 M Citric Acid, pH 2.6
Temperature: Ambient
Sample: Antibacterials
A B
Less solvent consumption,
less waste
0
1
2
3
4
5
Time (min)
www.agilent.com/chem/supplies
6
40
0
1
2
ZORBAX Solvent Saver
3
1. Sulfamerazine
2. Furazolidone
3. Oxolinic Acid
4. Sulfadimethoxine
5. Sulfaquinoxaline
6. Nalidixic Acid
4
5
Time (min)
This separation of antibacterials on a 4.6 and 3.0 mm ID columns, shows that solvent use is reduced by 50% just by changing to the Solvent Saver column with no change
in the chromatography. This reduces the cost of analyses dramatically.
6
40
LCSS001
LC and LC/MS
651