Safety evaluation of certain food additives - ipcs inchem

PHYTOSTEROLS, PHYTOSTANOLS AND THEIR ESTERS 157
6. REFERENCES
Abramsson-Zetterberg, L., Svensson, M. & Johnsson, L. (2007) No evidence of genotoxic
effect in vivo of the phytosterol oxidation products triols and epoxides. Toxicol. Lett., 173,
132–139.
Appel, M.J. (1998a) Acute oral toxicity study (limit study) with WD-041T97 in rats. Zeist,
Netherlands, TNO Nutrition and Food Research Institute (TNO Report V98.212).
Appel, M.J. (1998b) Acute dermal toxicity study (limit study) with WD-041T97 in rats. Zeist,
Netherlands, TNO Nutrition and Food Research Institute (TNO Report V98.213).
Appel, M.J. (1998c) Acute dermal irritation/corrosion study with WD-041T97 in albino
rabbits. Zeist, Netherlands, TNO Nutrition and Food Research Institute (TNO Report
V98.214).
Appel, M.J. (1998d) Acute eye irritation/corrosion study with WD-041T97 in albino rabbits.
Zeist, Netherlands, TNO Nutrition and Food Research Institute (TNO Report V98.215).
Appel, M.J. (1998e) Acute oral toxicity study (limit study) with PU-029P97 in rats. Zeist,
Netherlands, TNO Nutrition and Food Research Institute (TNO Report V98.217).
Appel, M.J. (1998f) Acute dermal toxicity study (limit study) with PU-029P97 in rats. Zeist,
Netherlands, TNO Nutrition and Food Research Institute (TNO Report V98.218).
Appel, M.J. (1998g) Acute dermal irritation/corrosion study with PU-029P97 in albino rabbits.
Zeist, Netherlands, TNO Nutrition and Food Research Institute (TNO Report V98.219).
Appel, M.J. (1998h) Acute eye irritation/corrosion study with PU-029P97 in albino rabbits.
Zeist, Netherlands, TNO Nutrition and Food Research Institute (TNO Report V98.220).
Assmann, G., Cullen, P., Erbey, J., Ramey, D.R., Kannenberg, F. & Schulte, H. (2006) Plasma
sitosterol elevations are associated with an increased incidence of coronary events in men:
results of a nested case–control analysis of the Prospective Cardiovascular Münster
(PROCAM) study. Nutr. Metab. Cardiovasc. Dis., 161, 13–21.
Ayesh, R., Weststrate, J.A., Drewitt, P.N. & Hepburn, P.A. (1999) Safety evaluation of
phytosterol esters. Part 5. Faecal short-chain fatty acid and microflora content, faecal
bacterial enzyme activity and serum female sex hormones in healthy normolipidaemic
volunteers consuming a controlled diet either with or without a phytosterol ester–enriched
margarine. Food Chem. Toxicol., 37, 1127–1138.
Baker, V.A., Hepburn, P.A., Kennedy, S.J., Jones, P.A., Lea, L.J., Sumpter, J.P. & Ashby, J.
(1999) Assessment of oestrogenicity using a combination of in vivo and in vitro assays.
Food Chem. Toxicol., 37, 13–22.
Boberg, K.M., Lund, E., Ölund, J. & Björkhem, I. (1990) Formation of C21 bile acids from plant
sterols in the rat. J. Biol. Chem., 265, 7967– 7975.
Bradford, P.G. & Awad, A.B. (2007) Phytosterols as anticancer compounds. Mol. Nutr. Food
Res., 51, 161–170.
Chan, Y.M., Varady, K.A., Lin, Y., Trautwein, E., Mensink, R.P., Plat, J. & Jones, P.J. (2006)
Plasma concentrations of plant sterols: physiology and relationship with coronary heart
disease. Nutr. Rev., 64, 385–402.
Clifton, P.M., Noakes, M., Ross, D., Fassoulakis, A., Cehun, M. & Nestel, P. (2004) High
dietary intake of phytosterol esters decreases carotenoids and increases plasma plant
sterol levels with no additional cholesterol lowering. J. Lipid Res., 45, 1493–1499.
Codex Alimentarius Commission (2007a) Report of the Thirty-ninth Session of the Codex
Committee on Food Additives, Beijing, China, 24–28 April. Rome, Italy, Food and
Agriculture Organization of the United Nations (ALINORM 07/30/12 Rev.; http://
www.codexalimentarius.net/web/archives.jsp?year=07).
Codex Alimentarius Commission (2007b) Procedural manual, 17th ed. Rome, Italy, World
Health Organization and Food and Agriculture Organization of the United Nations (http://
www.fao.org/docrep/010/a1472e/a1472e00.htm).