Safety evaluation of certain food additives - ipcs inchem

548 HYDROXY- AND ALKOXY-SUBSTITUTED BENZYL DERIVATIVES (addendum)
King, M.-T. (2002) Mutagenicity study of HR 02/G05025 in the Salmonella typhimurium/
mammalian microcosm reverse mutation assay (Ames-Test). Project No. AM.602N.
Unpublished report by Freiburger Labor für Mutagenitätsprüfung, Kirchzarten, Germany,
for the Flavor and Extract Manufacturers Association, Washington, DC, USA. Submitted
to WHO by the International Organization of the Flavour Industry, Brussels, Belgium.
Lina, B.A.R. (1999) Sub-chronic (13-week) oral toxicity study with 4-MBA in rats. Project
No. 481136. Unpublished report by TNO Nutrition and Food Research Institute, Zeist,
Netherlands, for the Flavor and Extract Manufacturers Association, Washington, DC, USA.
Submitted to WHO by the International Organization of the Flavour Industry, Brussels,
Belgium.
Meuling, W. & de Bie, A.T.H.J. (1999) Urinary excretion of 4-MBA and metabolites in human
volunteers after oral administration of 4-MBA. Project No. 40792. Unpublished report by
TNO Nutrition and Food Research Institute, Zeist, Netherlands, for the Flavor and Extract
Manufacturers Association, Washington, DC, USA. Submitted to WHO by the International
Organization of the Flavour Industry, Brussels, Belgium.
Nijssen, B., van Ingen-Visscher, K. & Donders, J. (2007) VCF (Volatile Compounds in Foods)
database. Zeist, Netherlands, TNO Nutrition and Food Research (http://www.vcf-online.nl/
VcfHome.cfm; Version 9.2 accessed September 2007).
Reitz, G. (1995) Hydrolysis of vanillin TK-10 acetal (TAK#935011). Unpublished report to the
Flavor and Extract Manufacturers Association, Washington, DC, USA. Submitted to WHO
by the International Organization of the Flavour Industry, Brussels, Belgium.
Van Delft, J.H.M. (1998a) Gene mutation test at the TK-locus of L5178Y cells with 4-MBA.
Project No. 480041/001. Unpublished report by TNO Nutrition and Food Research
Institute, Zeist, Netherlands, for the Flavor and Extract Manufacturers Association,
Washington, DC, USA. Submitted to WHO by the International Organization of the Flavour
Industry, Brussels, Belgium.
Van Delft, J.H.M. (1998b) Bacterial gene mutation test with 4-MBA. Project No. 480064/002.
Unpublished report by TNO Nutrition and Food Research Institute, Zeist, Netherlands, for
the Flavor and Extract Manufacturers Association, Washington, DC, USA. Submitted to
WHO by the International Organization of the Flavour Industry, Brussels, Belgium.
Van Delft, J.H.M. & de Vogel, N. (1998) Chromosome aberration test with 4-MBA in cultured
Chinese hamster ovary cells. Project No. 480040/001. Unpublished report by TNO
Nutrition and Food Research Institute, Zeist, Netherlands, for the Flavor and Extract
Manufacturers Association, Washington, DC, USA. Submitted to WHO by the International
Organization of the Flavour Industry, Brussels, Belgium.
Wolterbeek, A.P.M. & Waalkens-Berendsen, D.H. (1999) Oral embryotoxicity/teratogenicity
study with 4-MBA in rats. Project No. 481144. Unpublished report by TNO Nutrition and
Food Research Institute, Zeist, Netherlands, for the Flavor and Extract Manufacturers
Association, Washington, DC, USA. Submitted to WHO by the International Organization
of the Flavour Industry, Brussels, Belgium.