Safety evaluation of certain food additives - ipcs inchem

ALIPHATIC BRANCHED-CHAIN SATURATED AND UNSATURATED ALCOHOLS 319
Table 5 (contd)
No. Flavouring agent End-point Test object Concentration Results Reference
Up to 1000 μg/plate, ±S9 Negativea Lijinsky & Andrews
(1980)
Reverse mutation S. typhimurium TA98, TA100,
TA1535, TA1537 and TA1538
1834 Methyl 2-methyl-
2-propenoate
Up to 2300 or 5000 μg/ml, Negative
±S9
a Hachitani et al. (1981)
150–4700 μg/plate, ±S9 Negativea,g Hachitani et al. (1982)
Reverse mutation S. typhimurium TA98, TA100,
TA1535, TA1537 and TA1538
1834 Methyl 2-methyl-
2-propenoate
Reverse mutation S. typhimurium TA98, TA100,
TA1535, TA1537 and TA1538
1834 Methyl 2-methyl-
2-propenoate
40–10 000 μg/plate, ±S9 Negativea Waegemaekers &
Bensink (1984)
Reverse mutation S. typhimurium TA98, TA100,
TA1535, TA1537 and TA1538
1834 Methyl 2-methyl-
2-propenoate
100–10 000 μg/2 ml, ±S9 Negativea Waegemaekers &
Bensink (1984)
Reverse mutation S. typhimurium TA100 (liquid
incubation assay)
1834 Methyl 2-methyl-
2-propenoate
33–10 000 μg/plate Negativea National Toxicology
Program (1986)
Reverse mutation S. typhimurium TA97, TA98,
TA100 and TA1535
1834 Methyl 2-methyl-
2-propenoate
10–10 000 μg/plate, ±S9 Negative a Zeiger et al. (1987)
Reverse mutation S. typhimurium TA98, TA100,
TA1535 and TA1537
1834 Methyl 2-methyl-
2-propenoate
33–6666 μg/plate, ±S9 Negative a Zeiger et al. (1987)
Reverse mutation S. typhimurium TA97, TA98,
TA100 and TA1535
1834 Methyl 2-methyl-
2-propenoate
10–10 000 μg/plate Negative a Zeiger (1990)
Reverse mutation S. typhimurium TA97, TA98,
TA100, TA1535 and TA1537
1834 Methyl 2-methyl-
2-propenoate