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Safety evaluation of certain food additives - ipcs inchem

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536 HYDROXY- AND ALKOXY-SUBSTITUTED BENZYL DERIVATIVES (addendum)<br />

Table 1 (contd)<br />

Conclusion based<br />

on current estimated<br />

intake<br />

Comments on<br />

predicted metabolism<br />

Flavouring agent No. CAS No. and structure Step A3d Does intake exceed<br />

the threshold for<br />

human intake?<br />

See note 2 No safety concern<br />

No<br />

Europe: 0.01<br />

USA: 4<br />

Japan: ND<br />

Sodium 4-methoxybenzoyloxyacetate 1880 17114-82-8<br />

O<br />

O<br />

Na +<br />

-<br />

O<br />

O<br />

O<br />

See note 2 No safety concern<br />

No<br />

Europe: 88<br />

USA: 0.5<br />

Japan: 54<br />

Vanillin propylene glycol acetal 1882 68527-74-2<br />

O<br />

O<br />

OH<br />

O<br />

See note 2 No safety concern<br />

No<br />

Europe: 0.01<br />

USA: 2.2<br />

Japan: ND<br />

4-Methoxybenzoyloxyacetic acid 1883 10414-68-3<br />

O<br />

HO<br />

O<br />

O<br />

O

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