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Safety evaluation of certain food additives - ipcs inchem

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ETHYL LAUROYL ARGINATE 83<br />

Huntingdon, Cambridgeshire, England. Submitted to WHO by Laboratorios Miret S.A.,<br />

Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2000b) L.A.E.: acute dermal toxicity to the rat. Unpublished<br />

report No. LMA 019/002882/AC from Huntingdon Life Sciences Ltd, Huntingdon,<br />

Cambridgeshire, England. Submitted to WHO by Laboratorios Miret S.A., Barcelona,<br />

Spain.<br />

Huntingdon Life Sciences Ltd (2000c) ELA: dose range finding/palatability study by dietary<br />

administration to Han Wistar rats for 4 weeks. Unpublished report No. LMA 030/000063<br />

from Huntingdon Life Sciences Ltd, Huntingdon, Cambridgeshire, England. Submitted to<br />

WHO by Laboratorios Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2001a) ELA: bacterial mutation assay. Unpublished report No.<br />

LMA 038/012403 from Huntingdon Life Sciences Ltd, Huntingdon, Cambridgeshire,<br />

England. Submitted to WHO by Laboratorios Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2001b) ELA: in vitro mammalian chromosome aberration test<br />

in human lymphocytes. Unpublished report No. LMA 039/012517 from Huntingdon Life<br />

Sciences Ltd, Huntingdon, Cambridgeshire, England. Submitted to WHO by Laboratorios<br />

Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2001c) ELA: toxicity study by dietary administration to Han<br />

Wistar rats for 13 weeks. Unpublished report No. LMA 031/004276 from Huntingdon Life<br />

Sciences Ltd, Huntingdon, Cambridgeshire, England. Submitted to WHO by Laboratorios<br />

Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2001d) N--Lauroyl-L-arginine ethyl ester monohydrochloride:<br />

in vivo and in vitro metabolism in the rat. Unpublished report No. LMA 033/012117 from<br />

Huntingdon Life Sciences Ltd, Huntingdon, Cambridgeshire, England. Submitted to WHO<br />

by Laboratorios Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2003a) N -Lauroyl-L-arginine ethyl ester monohydrochloride:<br />

in vitro stability. Unpublished report No. LMA 043/032898 from Huntingdon Life Sciences<br />

Ltd, Huntingdon, Cambridgeshire, England. Submitted to WHO by Laboratorios Miret S.A.,<br />

Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2003b) ELA: preliminary study <strong>of</strong> effects on reproductive<br />

performance in CD rats by dietary administration. Unpublished report No. LMA 041/032575<br />

from Huntingdon Life Sciences Ltd, Huntingdon, Cambridgeshire, England. Submitted to<br />

WHO by Laboratorios Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2004) ELA: in vitro mutation test using mouse lymphoma<br />

L5178Y cells. Unpublished report No. LMA 052/042549 from Huntingdon Life Sciences<br />

Ltd, Huntingdon, Cambridgeshire, England. Submitted to WHO by Laboratorios Miret S.A.,<br />

Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2005a) Lauric arginate toxicity study by dietary administration<br />

to CD rats for 52 weeks. Unpublished report No. LMA 050/042556 from Huntingdon Life<br />

Sciences Ltd, Huntingdon, Cambridgeshire, England. Submitted to WHO by Laboratorios<br />

Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2005b) ELA: two generation reproductive performance study<br />

by dietary administration to CD rats. Unpublished report No. LMA 042/032553 from<br />

Huntingdon Life Sciences Ltd, Huntingdon, Cambridgeshire, England. Submitted to WHO<br />

by Laboratorios Miret S.A., Barcelona, Spain.<br />

Huntingdon Life Sciences Ltd (2005c) Lauric arginate pharmacokinetics in rats. Unpublished<br />

report No. LMA 057/053626 from Huntingdon Life Sciences Ltd, Huntingdon,<br />

Cambridgeshire, England. Submitted to WHO by Laboratorios Miret S.A., Barcelona,<br />

Spain.<br />

Huntingdon Research Centre Ltd (1995a) Mirenat-N: acute oral toxicity to the rat. Unpublished<br />

report No. LMA 4/951314/AC from Huntingdon Research Centre Ltd, Huntingdon,

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