Safety evaluation of certain food additives - ipcs inchem

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ALIPHATIC LINEAR ,-UNSATURATED ALDEHYDES 341 Table 2 (contd) Flavouring agent (No.) Most recent annual volume (kg) a (E,Z)-Hept-2-en-1-yl isovalerate (1799) Intake b Annual μg/day μg/kg bw per day volume from natural occurrence in <strong>food</strong>s (kg) c Europe 0.1 0.01 0.0002 USA 44 5 0.09 NA Japan trans-2-Hexenal glyceryl acetal (1800) ND ND ND Europe ND ND ND USA ND ND ND NA Japan trans-2-Hexenal propylene glycol acetal (1801) 12 3 0.05 Europe ND ND ND USA ND ND ND NA Japan cis- and trans-1- Methoxy-1-decene (1802) 394 104 2 Europe 0.1 0.01 0.0002 USA 1 0.1 0.002 NA Japan (E)-Tetradec-2-enal (1803) ND ND ND Europe 0.1 0.01 0.0002 USA 0.6 0.07 0.001 1976e 3293 Japan (E)-2-Pentenoic acid (1804) ND ND ND Europe 0.1 0.01 0.0002 USA ND ND ND NA Japan 0.1 0.03 0.0004 Consumption ratio d
342 ALIPHATIC LINEAR ,-UNSATURATED ALDEHYDES Table 2 (contd) Flavouring agent (No.) Most recent annual volume (kg) a (E)-2-Octenoic acid (1805) Intake b Annual μg/day μg/kg bw per day volume from natural occurrence in <strong>food</strong>s (kg) c Europe 0.1 0.01 0.0002 USA ND ND ND + NA Japan Ethyl trans-2butenoate (1806) 0.1 0.03 0.00 Europe 115 12 0.2 USA 43 5 0.1 96 2 Japan Hexyl 2-butenoate (1807) 134 35 0.6 Europe 21 2 0.04 USA ND ND ND + NA Japan Ethyl trans-2hexenoate (1808) 0.1 0.03 0.0004 Europe 171 18 0.3 USA 0.1 0.02 0.0003 4 40 Japan (E,Z)-Methyl 2hexenoate (1809) 36 10 0.2 Europe 0.3 0.03 0.001 USA 288 35 0.6 + NA Japan Hexyl trans-2hexenoate (1810) 0.3 0.08 0.001 Europe 0.1 0.01 0.0002 USA 2 0.2 0.004 + NA Japan ND ND ND Consumption ratio d
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WHO FOOD ADDITIVES SERIES: 60 Safet
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CONTENTS Preface ..................
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PREFACE The monographs contained in
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ASPARAGINASE FROM ASPERGILLUS NIGER
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16 CALCIUM LIGNOSULFONATE (40-65) 1
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18 CALCIUM LIGNOSULFONATE (40-65) ~
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20 CALCIUM LIGNOSULFONATE (40-65) A
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22 CALCIUM LIGNOSULFONATE (40-65) c
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24 CALCIUM LIGNOSULFONATE (40-65) T
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28 CALCIUM LIGNOSULFONATE (40-65) i
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ETHYL LAUROYL ARGINATE First draft
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ETHYL LAUROYL ARGINATE 41 and Devel
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ETHYL LAUROYL ARGINATE 43 lauroyl a
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ETHYL LAUROYL ARGINATE 45 arginine.
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ETHYL LAUROYL ARGINATE 47 resulting
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ETHYL LAUROYL ARGINATE 49 Table 4.
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ETHYL LAUROYL ARGINATE 51 weight ch
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ETHYL LAUROYL ARGINATE 53 stomach l
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ETHYL LAUROYL ARGINATE 55 fibrosis
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ETHYL LAUROYL ARGINATE 57 Table 5 (
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ETHYL LAUROYL ARGINATE 59 first 4 d
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ETHYL LAUROYL ARGINATE 61 The gener
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ETHYL LAUROYL ARGINATE 63 treatment
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ETHYL LAUROYL ARGINATE 65 gestation
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ETHYL LAUROYL ARGINATE 67 Body weig
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ETHYL LAUROYL ARGINATE 69 Table 6.
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ETHYL LAUROYL ARGINATE 77 About 99%
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ETHYL LAUROYL ARGINATE 79 concentra
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ETHYL LAUROYL ARGINATE 81 theoretic
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ETHYL LAUROYL ARGINATE 83 Huntingdo
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PAPRIKA EXTRACT First draft prepare
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PAPRIKA EXTRACT 87 of capsanthin ra
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PAPRIKA EXTRACT 89 biochemical para
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PAPRIKA EXTRACT 91 Table 1. Sales o
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PAPRIKA EXTRACT 93 Table 2. Estimat
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PAPRIKA EXTRACT 95 The European Sci
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PAPRIKA EXTRACT 97 The potential di
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PAPRIKA EXTRACT 99 Hornero-Mendez,
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PAPRIKA EXTRACT 101 Appendix 1. Res
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PAPRIKA EXTRACT 103 Appendix 1. (co
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PAPRIKA EXTRACT 105 Appendix 1. (co
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108 PHOSPHOLIPASE C EXPRESSED IN PI
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PHYTOSTEROLS, PHYTOSTANOLS AND THEI
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166 POLYDIMETHYLSILOXANE (addendum)
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STEVIOL GLYCOSIDES (addendum) First
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STEVIOL GLYCOSIDES (addendum) 185 r
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STEVIOL GLYCOSIDES (addendum) 187 c
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STEVIOL GLYCOSIDES (addendum) 189 a
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STEVIOL GLYCOSIDES (addendum) 191 N
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STEVIOL GLYCOSIDES (addendum) 193 2
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STEVIOL GLYCOSIDES (addendum) 195 T
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STEVIOL GLYCOSIDES (addendum) 197 a
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STEVIOL GLYCOSIDES (addendum) 199 r
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STEVIOL GLYCOSIDES (addendum) 201 l
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STEVIOL GLYCOSIDES (addendum) 203 g
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STEVIOL GLYCOSIDES (addendum) 209 t
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STEVIOL GLYCOSIDES (addendum) 211 t
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STEVIOL GLYCOSIDES (addendum) 213 s
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STEVIOL GLYCOSIDES (addendum) 215 C
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STEVIOL GLYCOSIDES (addendum) 217 L
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STEVIOL GLYCOSIDES (addendum) 219 W
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222 SULFITES: ASSESSMENT OF DIETARY
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SAFETY EVALUATIONS OF GROUPS OF REL
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264 INTRODUCTION Figure 1. Procedur
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DIETARY EXPOSURE ASSESSMENT OF FLAV
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Page 299 and 300: 292 ALIPHATIC BRANCHED-CHAIN SATURA
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ALKOXY-SUBSTITUTED ALLYLBENZENES 39
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FURAN-SUBSTITUTED ALIPHATIC HYDROCA
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HYDROXY- AND ALKOXY-SUBSTITUTED BEN
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MISCELLANEOUS NITROGEN-CONTAINING S
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580 SUBSTANCES STRUCTURALLY RELATED
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ANNEXES
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598 ANNEX 1 10. Specifications for
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600 ANNEX 1 No. 54, 1974; WHO Techn
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602 ANNEX 1 70. Evaluation of certa
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604 ANNEX 1 108. Toxicological eval
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606 ANNEX 1 148. Residues of some v
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608 ANNEX 1 188. Safety evaluation
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610 ANNEX 2 ECG electrocardiogram E
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612 ANNEX 2 SI stimulation index SU
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614 ANNEX 3 Ms J. Baines, Food Stan
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ANNEX 4 ACCEPTABLE DAILY INTAKES, O
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ANNEX 4 619 Food additive Specifica
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ANNEX 4 621 3. FLAVOURING AGENTS 3.
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ANNEX 4 623 Flavouring agent No. Sp
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ANNEX 4 625 Flavouring agent JECFA
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ANNEX 4 627 Actual production volum
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ANNEX 4 629 Flavouring agent No. Sp
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ANNEX 5 SUMMARY OF THE SAFETY EVALU
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ANNEX 5 633 Secondary components Co
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