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Safety evaluation of certain food additives - ipcs inchem

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460 ALKOXY-SUBSTITUTED ALLYLBENZENES<br />

APPENDIX 1. ALKOXY-SUBSTITUTED ALLYLBENZENES<br />

IN HERBS AND SPICES<br />

Explanation <strong>of</strong> Appendix 1<br />

The tables in Appendix 1 for estragole, methyl eugenol, safrole, myristicin,<br />

elemicin and apiole provide data on the content <strong>of</strong> each <strong>of</strong> these alkoxy-substituted<br />

allylbenzenes within spices, herbs and spice and herb oils. Each table is organized<br />

into sections, as described below.<br />

Section 1 provides a list <strong>of</strong> the spices and herbs for which data were<br />

compiled.<br />

Section 2 provides the lower limit, upper limit and mean value for the volatile<br />

oil content within each spice and herb. Data for this were collected from a variety <strong>of</strong><br />

sources, including internal industry data and published reports regarding essential<br />

oil content in a variety <strong>of</strong> herbs and spices.<br />

Section 3 provides the mean, the number <strong>of</strong> data points, and the lower and<br />

upper limits for the content <strong>of</strong> the alkoxy-substituted allylbenzene within the volatile<br />

oil. Data for this were also collected from a variety <strong>of</strong> sources, including internal<br />

industry data and published reports regarding essential oil compositions.<br />

Section 4 provides the lower limit, upper limit and mean values for the<br />

content <strong>of</strong> each alkoxy-substituted allylbenzene within each herb/spice product.<br />

Each value in this section was calculated by multiplying the volatile oil content (within<br />

the herb/spice product) by the alkoxy-substituted allylbenzene content (within the<br />

volatile oil). For instance, to calculate the lower limit for the estragole content within<br />

basil, the lower limit for volatile oil content in basil (0.08%) is multiplied by the<br />

estragole content within the basil volatile oil (0.01%), resulting in a lower limit for<br />

estragole content <strong>of</strong> 0.08 mg/kg.<br />

Section 5 provides information concerning the amount <strong>of</strong> the alkoxysubstituted<br />

allylbenzene present in each herb- or spice-derived essential oil product<br />

that has been used as a flavouring. The first column in this section provides data<br />

for herb- and spice-derived essential oil poundage that were collected by the Flavor<br />

and Extract Manufacturers Association in their most recent (2005) poundage survey<br />

(Gavin et al., 2007). Based on this reported essential oil poundage, the next three<br />

columns provide the lower limit, upper limit and mean value for each alkoxysubstituted<br />

allylbenzene volume that would be present in each herb- and spicederived<br />

essential oil as a flavouring agent. For instance, to calculate the upper limit<br />

for the estragole content (in kg) within the total amount <strong>of</strong> basil oil that was reported<br />

as being used as a flavouring agent, the upper limit for estragole content in basil oil<br />

(91.52%) is multiplied by the volume <strong>of</strong> basil oil used as a flavouring agent (828 kg).<br />

This calculation results in an estragole volume <strong>of</strong> 757.8 kg arising from its presence<br />

within basil oil used as a flavouring agent.<br />

Section 6 provides information concerning the amount <strong>of</strong> the alkoxysubstituted<br />

allylbenzene present in each herb or spice product that was imported<br />

into the USA in the 2007 calendar year. The first column in this section provides<br />

data for herbs and spices that were collected by the United States Department <strong>of</strong>

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