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LIVE POLIO IRUS VACCINES

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Effectiveness of Trivalent Vaccine in Immunizing Young Children<br />

119<br />

TABLE 6.<br />

d MARKERS OF 40 STRAINS FROM VACCINEES AND CONTACTS<br />

WEEKS P VACCINATION TOTAL<br />

TYPE SOURCE 1-2 3-4 6-7 STRAINS<br />

D- i D+ D- I D+ D- í D+ TESTED<br />

12 VACCINEES I O O 3 4 0 4 3 0 15<br />

II CONTACTS 1 4 .I 0 6 1 13<br />

3 VACCINEES 2 1 0 3<br />

I CONTACT 0 I 0 I<br />

5 VACCINEES 4 0 0 I I I 7<br />

I1 CONTACT 1 0 0<br />

Dr. Juan A. Montoya, Pan American Sanitary<br />

Bureau Epidemiology Consultant, and Dr. Joaquín<br />

Nufiez, Technical Director, National Campaign<br />

against Poliomyelitis, Costa Rica; also to<br />

Mrs. María José Ramírez Vargas and Miss Jael<br />

Chacón Zamora, Santo Domingo de Heredia<br />

Health Center, and Mrs. Mary Morales, Ministry<br />

of Health, San José, Costa Rica. Without the<br />

cooperation of these individuals this study would<br />

not have been possible.<br />

REFERENCES<br />

1. Prem, K. A., and McKelvey, J. L.: Antibody<br />

response in adults and children following<br />

simultaneous oral administration of three<br />

type strains of live attenuated poliomyelitis<br />

virus. In: Live Poliovirus Vaccines, First<br />

International Conference. Scient. Pub. no.<br />

44 of the Pan American Health Organization,<br />

pp. 249-253, 1959.<br />

2. Cox, H., Cabasso, V. J., et al.: Immunologic<br />

response to trivalent oral poliomyelitis vaccine.<br />

In: Live Poliovirus Vaccines, First<br />

International Conference. Scient. Pub. no.<br />

44 of the Pan American Health Organization,<br />

pp. 229-248, 1959.<br />

3. Chumakov, M. P., Voroshilova, M. K., et al.:<br />

Preliminary report on mass oral immunization<br />

of population against poliomyelitis with<br />

live virus vaccine from A. B. Sabin's attenuated<br />

strains. In: Live Poliovirus Vaccines,<br />

First International Conference. Scient. Pub.<br />

no. 44 of the Pan American Health Organization,<br />

pp. 517-529, 1959.<br />

4. Smorodintsev, A. A., Ilyenko, V. I., et al.:<br />

Part 2. Virological and immunological characteristics<br />

of vaccinal infection in children<br />

inoculated per os with a live poliomyelitis<br />

vaccine made from the Sabin strains. In:<br />

Live Poliovirus Vaccines, First International<br />

Conference. Scient. Pub. no. 44 of the Pan<br />

American Health Organization, pp. 312-323,<br />

1959.<br />

5. Prem, K. A., McKelvey, J. L., and Fergus, J.:<br />

Immunologic response of infants under six<br />

months of age to oral trivalent poliomyelitis<br />

vaccine. In: Live Poliovirus Vaccines, First<br />

International Conference. Scient. Pub. no.<br />

44 of the Pan American Health Organization,<br />

pp. 254-259, 1959.<br />

6. - , , - : Immunologic response<br />

of pregnant women to oral trivalent<br />

poliomyelitis vaccine. In: Live Poliovirus<br />

Vaccines, First International Conference.<br />

Scient. Pub. no. 44 of the Pan American<br />

Health Organization, pp. 260-269, 1959.

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