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LIVE POLIO IRUS VACCINES

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488 Efficacy-Field Evidence<br />

-<br />

TABLE 2. NUMBER OF PERSONS IN THE VACCINATED AND CONTROL GROUPS IN THE BYELORUSSIAN<br />

SSR, LATVIAN SSR AND MOLDAVIAN SSR AND IN THE NOVGOROD AND PSKOV OBLASTS IN 1959<br />

REGION<br />

AGE<br />

GROUPS<br />

No. OF PERSONS<br />

VACCINATED INTERNAL CONTROL EXTERNAL CONTROL.<br />

9 months to 3 years 74,868 77,612 344,076<br />

Byelorussian 3-7 years 119,897 152,353 614,350<br />

SSR 7-14 years 347,754 85,371 977,375<br />

Total 542,519 315,336 1,935,801<br />

9 months to 3 years 72,274 37,744 ]07,277<br />

Moldavian 3- 7 years 80,551 26,870 109,500<br />

SSR 7-14 years 201,782 57,059 164,857<br />

Total 354,607 121,673 381,634<br />

9 months to 3 years 27,840 56,065 32,103<br />

Latvian 3- 7 years 55,349 22,652 35,744<br />

SSR 7-14 years 159,751 18,055 73,488<br />

14-30 years 177,604 10,013<br />

Total 420,544 106,785 141,335<br />

9 months to 3 years 49,292 7,133<br />

Pskov 3- 7 years 45,699 6,526<br />

Oblast 7-15 years 102,843 21,594<br />

Total 197,834 35,253 -<br />

9 months to 3 years 41,438 6,979<br />

Novgorod 3- 7 years 39,990 3,970<br />

Oblast 7-15 years 80,341 13,875<br />

Total 161,769 24,824<br />

Grand total 1,677,273 603,873 2,458,770<br />

tiveness of live and killed vaccine under comparable<br />

epidemiological conditions.<br />

The distribution of the vaccinated and control<br />

groups in the various Republics. In the Byelorussian<br />

Republic, 542,519 city children up to<br />

14 years of age were immunized. This corresponded<br />

to 63 per cent of the total number of<br />

children in the cities. The remaining 37 per<br />

cent (315,336) formed the internal control<br />

group. The children in the rural areas, who<br />

were two-and-a-half times as numerous as the<br />

urban child population of the same age, were not<br />

given the live vaccine; they constituted the external<br />

control group. In previous years, the<br />

absolute number of poliomyelitis cases was<br />

similar among the rural and urban groups of<br />

children, which explains the lower percentage<br />

indices for poliomyelitis in rural localities in<br />

those years 0<br />

In the Moldavian SSR the vaccination campaign<br />

covered 13 central rayons of the Republic<br />

and the four large cities situated there, which<br />

accounts for more than half the population of<br />

the Republic and in which, in the previous years,<br />

about 50 per cent of the annual number of poliomyelitis<br />

cases in the Republic had been recorded.<br />

A total of 354,607 children and young people<br />

aged between nine months and 14 years were<br />

vaccinated; 106,872 formed the internal control<br />

(contact) group. The third group consisted<br />

of 381,634 persons of the same age and<br />

constituted the external control group.<br />

In the Latvian SSR 420,544 children and<br />

adults up to 30 years of age were vaccinated in<br />

Riga City and in a number of rayons in the<br />

Republic.' 8<br />

The 106,872 children in the contact groups left<br />

unvaccinated in the regions where the live vaccine<br />

was employed constituted the internal control.<br />

The population numbering 41,336 between<br />

nine months and 18 years of age in rayons where<br />

live vaccine had not been administered represented<br />

the external control group.<br />

Somewhat later, in June and July 1959, 360,000<br />

children in the cities and settlements of the<br />

Novgorod and Pskov Oblasts up to 14 years of

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