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LIVE POLIO IRUS VACCINES

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Epidemiological, Virological Survey Following Oral Administration 135<br />

539 586 353 368<br />

200<br />

190<br />

180<br />

170<br />

160<br />

150<br />

140<br />

130<br />

120 1I<br />

110 I /<br />

100 t<br />

90 -<br />

80 1'<br />

60 I V<br />

11 1<br />

40 ¡ 195 6-<br />

1: ~ * 1955 .. ..<br />

50 1<br />

1 po<br />

1<br />

1955<br />

30<br />

11 III IV V VI VII VIIl IX X Xl XII MONTH<br />

Fic. 1. Number of reported cases of poliomyelitis in The Netherlands, 1955.1959.<br />

tion trials, neither in Region I, nor in the other been reported in Region I, which are reflected in<br />

regions.<br />

a relatively high morbidity rate in an area with<br />

This is also evident from the morbidity rates a population of only 150,000. Poliovirus Type 2<br />

as recorded in Fig. 4, with the exception, how- has been isolated from two of these cases, but<br />

ever, of the fourth three-month period of 1959 the other two were probably not due to polioin<br />

Region I. During this period, four cases have virus infection, since we failed to isolate virus

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