LIVE POLIO IRUS VACCINES

254
TABLE 21.
Efficacy-Laboratory Evidence
ANTIBODY TITERS IN CHILDREN DEVELOPING ANTIBODY ONE MONTH AFTER ONE FEEDING
WITH TRIVALENT LIVE VACCINE
---
ANTIBODY DEVELOPMENT TO
1:4
1:8
SERUM DILUTION
TYPE 1 TYPE 2 TYPE 3
No. OF No. OF NO. OF
CHILDREN % CHILDREN % CHILDREN %
7 8.4 1 1.2 8 10.4
9 10.8 12 14.3 7 9.1
1:16
16
19.3
13 15.5
24
31.1
1:32
18
21.7
14
___________________________________________________
I
16.7
15
19.5
1:64
9
10.8
17
20.2
7
9.1
1:128 17 20.5 6 7.1 11 14.3
1:256 and greater 7 8.4 21 25.0 5 6.5
Total: 83 100.0 84 100.0 77 100.0
AFTER IMMUNIZATION
1:512 _
* ooooo.
TOTAL 241
1:256 ®*
e. -
*e
.~ _******e.
1:128 Eoo
se.
1:64 *oo *o
= base·
ooooo"
1:32
_
_
-e-
1 :16 =
· m
1:8
1:4 _e
e.o 4
.
.
1:4
FIo. 5.
BEFORE IMMUNIZATION
1:4 1:4 1:8 1:16 1:32 1:64 1:128 1:256 1:512
76 10 12 28 25 35 13 39 3
Rise of Type 1 antibody titers one month after one feeding with live trivalent vaccine fromi
Sabin's strains (Moscow region).