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LIVE POLIO IRUS VACCINES

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Live Poliomyelitis Vaccine-Small-Scale Trial in Isolated Island Community 543<br />

TABLE 9.<br />

PRE- AND POST-VACCINATION STATUS OF 40 ANTIBODY NEGATIVES AMONG 201 PERSONS<br />

FED THE THREE TYPES OF ORAL <strong>POLIO</strong>MYELITIS VACCINE WITH 4-WEEK INTERVALS<br />

Pre-Vaccination<br />

Antibody Negatives<br />

(TYPE 2, TYPE 1, TYPE 3) IN 1959<br />

Negative to Type No. of Subjects Negative to Type Converted<br />

a<br />

Post-Vaccination Status<br />

1 ! 2 3<br />

1, 2, 3 2 - - - 2<br />

1, 2 2 - - - 2<br />

1, 3- - 2<br />

2,3 7 - 1 6<br />

1 8 1 - - 7<br />

2 .3 - - - 3<br />

3 16 - - 15<br />

Totals 40 1 1 2 37<br />

TABLE 10.<br />

FREQUENCY OF NON-IMMUNE SUBJECTS ON SOTTUNGA ISLAND AT VARIOUS STAGES<br />

DURING THE TRIALS IN 1958 AND 1959<br />

Date of Polio Vaccine Number Per Cent Non-Immune<br />

Saempling Used Tested<br />

Type 1 Type 2 Type 3<br />

January -58 196 39 53 46<br />

Inactivated<br />

April -58 195 25 19 31<br />

Live Type 1<br />

May -58 199 15 11 28<br />

July -58 176 14 10 30<br />

March -59 201 11 6 17<br />

_________________________201 ll 6 17___<br />

June -59<br />

Live Type 2,1,3<br />

196<br />

1.5<br />

_<br />

180 x 0.5<br />

2.0<br />

2.5<br />

-- t- - _t-<br />

0.5<br />

1.0<br />

xCorrected figures for persons who received all<br />

the three types in 1959.

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