LIVE POLIO IRUS VACCINES

456
Efficacy-Field Evidence
M.G. C F 28. A vaccinee who participated on
4-26-60. She became ill on 5-3 with sore throat,
fever, and headache. On 5-7 she experienced
difficulty in walking and was hospitalized. She
became psychotic. She had bilateral lower extremity
flaccid paralysis. The residual paralysis
probably will be marked. At present she is an
in-patient on the neuropsychiatric service.
G.L. WI M 20. A student with multiple congenital
anomalies who took vaccine on 3-2-60.
He became ill on 3-13. His presenting symptoms
were dysphagia, fever, sore throat, and vomiting.
The following day he developed a severe headache
and his difficulty in swallowing increased.
He was examined at a military hospital. It was
found that he had hypersthesia of the posterior
pharyngeal wall and absent gag reflexes hilaterally.
A tissue biopsy from the right hypopharynx
showed muscle atrophy. The diagnosis
made retrospectively on 5-4 by the physicians at
this hospital was "abortive poliomyelitis." Further
investigation is pending and this case is
being held as "diagnosis undetermined."
ACKNOWLEDGMENTS
Grateful acknowledgment is made to: Dr.
M. Michael Sigel, Director, Variety Research
Foundation; Miss Methyl I. Crossley, Director
of Nursing Service, Dade County Department of
Public Health, and to their staffs. Without the
help they have given this program, completion of
surveillance would have been impossible.