LIVE POLIO IRUS VACCINES

Course of Mass Immunization in USSR with Vaccine from Sabin's Strains 417
TABLE 4. ANTIBODY RESPONSE TO TYPE 1 (ONE AND FOUR MONTHS) AND TO TYPE 3 (ONE MONTH)
AFTER IMMUNIZATION OF CHILDREN UNDER Two YEARS OF ACE WITH LIVE VACCINE INCORPORATED
INTO DRACGÉE-CANDY STORED FOR THREE DAYS AT RooM TEMPERATURE (+220 C.)
(M. K. Voroshilova, G. P. Taranova, 1959)
ONE MONTH AFTER INGESTION OF
TYPE 1 VACCINE
FoUR MONTHS AFTER INGESTION OF
TYPE 1 AND ONE MONTH AFTER INGESTION OF
TYPE 3 VACCINE
NUMBER OF CHILDREN DEVELOPED NUMBER OF CHILDREN DEVELOPED
WITHOUT ANTIBODY ANTIBODY WITHOUT ANTIBODY ANTIBODY
TO TYPES No. % TO TYPES No. % o
1 ° 19 14 73.7 1 ° 15 12 80.0
2 ° 15 0 0 2 ° 14 0 0
3 ° 19 0 0 3 ° 15 9 60.0
TABLE 5. ANTIBODY RESPONSE 1.5 MONTHS AFTER IMMUNIZATION WITH TYPE 1 MONOVACCINE IN
DRAGIE-CANDY STORED UNDER DIFFERENT CONDITIONS (1959)
ANTIBODY 1.5 MONTHS AFTER IMMIUNIZATION
CONDITIONS
OF STORAGE
- 20°C
+22°C
PERIOD
OF
STORAGE
(DAYS)
3-30
3-7
No. OF
CHILDREN
IN CHILDREN WITHOUT
TYPE 1 ANTIBODY
DEVELOPED
ANTIBODY
'- l l ¡ l
15
23
13
18
86.7
78.3
No. OF
CHILDREN
10
17
IN TRIPLE-NEGATIVE
CHILDREN
DEVELOPED
ANTIBODY
8
13
80.0
76.5
Total
38
31
81.6
27
21
77.8
TABLE 6. DEVELOPMENT AND RISE OF ANTIBODY IN CHILDREN UNDER THREE YEARS, IMMUNIZED WITH
LIVE VACCINE IN DRAGÉE-CANDY (VACCINE STORED FOR 1-3 DAYS AT +200 C.)
(I. N. Dobrova, 1960, pH color test)
NUMBER OF CHILDREN
WITHOUT PRE-
VACCINATION
ANTIBODY
DEVELOPED
ANTIBODY
No. %
NUMBER
OF CHILDREN
WITH PRE-
VACCINATION
ANTIBODY
DEVELOPED
RISE IN
TITER
PER CENT
Type 1-22
Type 2-16
Type 3-23
17* 77.3
16 100.0
23 100.0
21
28
21
11
19
13
52.4
67.8
61.9
* Including two of five triple-negative children.