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LIVE POLIO IRUS VACCINES

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508 Efficacy-Field Evidence<br />

TABLE 1. VACCINATION STATUS IN CZECHOSLOVAKIA IN 1959<br />

(a) Number of children vaccinated with inactivated vaccine<br />

(Report through 1 July 1959)<br />

AGE<br />

No. OF<br />

INOCULA-<br />

CZECH REGIONS SLOVAKIA TOTAL<br />

GROUP TIONS NUMBER % NUMBER % NUMBER %<br />

0 160,833 11.0 130,380 16.0 291,263 12.8<br />

1 31,256 2.1 37,117 4.6 68,373 3.0<br />

1-9 2 128,197 8.7 87,590 10.8 215,787 9.5<br />

3 1,144,343 78.2 556,876 68.6 1,701,219 74.7<br />

2+3 1,272,540 86.9 644,466 79.4 1,917,006 84.2<br />

0 413,479 34.8 169,756 35.0 583,235 34.9<br />

1 12,710 1.1 10,995 2.3 23,705 1.4<br />

2 37,258 3.1 25,523 5.3 62,781 3.8<br />

3 725,941 61.0 277,782 57.4 1,003,723 59.9<br />

2+3 763,199 64.1 303,305 62.7 1,066,504 63.7<br />

(b)<br />

Number of children vaccinated with the fourth dose of Salk's vaccine in the region of Plzeii<br />

(April-May 1959)<br />

% FROM CHILDREN VACCINATED<br />

AGE GROUP NUMBER OF VACCINATED THREE TIMES<br />

2-10 years 49,058 68.7<br />

(c)<br />

Number of orally vaccinated children<br />

(December 1958-February 1959)<br />

TYPE 1 TYPES 1-3 TYPES 1-3-2<br />

AGE<br />

GROUP NUMBER %* NUMBER %* NUMBER %*<br />

2-6<br />

6-8<br />

Total<br />

114,064<br />

29,313<br />

143,377<br />

73.0<br />

34.0<br />

59.1<br />

101,487<br />

25,803<br />

127,290<br />

64.9<br />

29.9<br />

52.5<br />

90,386<br />

24,124<br />

114,510<br />

57.8<br />

28.0<br />

47.2<br />

* Percentage from number of children vaccinated three times with inactivated vaccine.<br />

on a mass scale). This strict delimitation of<br />

the experimental areas has the disadvantage that<br />

it does not permit (in view of the relatively<br />

small area of the regions) more general epidemiological<br />

conclusions. I feel, however, that for<br />

the purpose of our investigations, this method<br />

was more suitable than the very variable experimental<br />

conditions in the entire population, which<br />

would not be appropriate, particularly when<br />

using the live vaccine,

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