LIVE POLIO IRUS VACCINES

478
Efficacy-Field Evidence
TABLE 7. RODRIGUES-IMMUNITY SURVEY 1957
TOTAL TYPE 1 TYPE 2 TYPE 3
AGE GROur TESTED + - + - + -
0-3 yrs 45 0 45 0 45 0 45
4-10 yrs 41 3 38 38 3 32 9
11-15 yrs 28 7 21 28 0 23 5
16-20 yrs 8 2 6( 7 1 6 2
Over 20 10 8 2 1( 0 10 0
Post Salk Vaccine
0- 5 yrs 50 1 49 34 16 20 30
neither the vaccine nor transportation was available
until November.
While waiting, the epidemic struck Rodrigues.
1 think we are extremely lucky that transportation
was not available, since the infection was
apparently introduced by passengers arriving by
steamer from Mauritius in the middle of August.
The first paralytic case was reported on 25 September
1959, and the last case on 6 October.
Nine cases were reported. These were scattered
over the island. Two had previously been vaccinated
with Salk type vaccine, and seven had not
been vaccinated.
Trivalent vaccine prepared from Sabin's strains
by the Laboratories of the Poliomyelitis Research
Foundation arrived on the island on 8 November
and a mass vaccination campaign was carried out
under the direction of Dr. Chung Hin. Of the
total population of 17,603, 16,802 received the
vaccine, including the oldest inhabitant, a woman
of 103 years. No ill effects were reported after
vaccination.
For the assessment of the value of the vaccine,
pre- and post-vaccination bloods and
samples of pre-vaccination stool were collected.
These were refrigerated, taken by steamer to
Mauritius, and then flown by air to Johannesburg.
Laboratory Studies. The results of the laboratory
studies are summarized in Tables 8 and 9.
The post-epidemic but pre-feeding specimens
showed that all of those tested in this age group
TABLE 8.
VIRUS ISOLATION-RODRIGUES
No. OF STOOLS TESTED
4
No. POSITIVE
2 (Type 1)
NEGATIVE
2
TABLE 9.
PRE- AND POST-VACCINATION IMMUNITY, NOVEMBER 1959-RODRIGUES
AGE GRoUP
0-3 yrs
TOTAL
TESTED
33
Pre 33
Post 33
TYPE 1
o
o
23
27
TYPE 2
10
6
6
26
TYPE 3
27
7
4-10 yrs
56 Pre 56 0 48 8 42 14
Post 56 0 55 1 52 4
11-15 yrs
26 Pre 26
Post 26
0 26 0 26
0 26 0 26
o
O
16-20 yrs
Over 20
2 Pre 2 0 2 0 2 0
Post 2 0 2 0 2 0
0