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LIVE POLIO IRUS VACCINES

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Index<br />

613<br />

Dosage-continued<br />

statistics, USSR, 418<br />

trivalent vaccine, optimum levels, 121<br />

"Double blind study"<br />

need for, 157<br />

no knowledge of vaccine or placebo, 461, 462<br />

Douglas, GQrdon W., 321<br />

DPT inoculation, 328, 597-598<br />

Dragée-candy, 241, 264, 414<br />

advantages, 419, 577, 585<br />

Drobyshevskaya, A. I., paper, 482-501<br />

Drozdov, S. G., paper 413-428; 416<br />

Duben, J., paper 228-239<br />

Dulbecco method<br />

plaque technique, 34<br />

Dulbecco, Renato, 5, 7, 47, 49-50, 109-110, 268, 328-<br />

329, 480, 505, 574<br />

Dulutlh<br />

mass trial, 21,000 participants, 461<br />

DuPan, R. Martin, 322, 323<br />

Dyes<br />

photodynamic action, destruction of B virus, 87<br />

Dysentery<br />

carrier vs. disseminator, 410<br />

Dzagurov, S. G., paper, 413-428<br />

E 206, see Poliomyelitis virus, Type 1, E 206<br />

E marker, see Elution marker<br />

Earle's solution, 125, 229<br />

East Germany, see German Democratic Republic<br />

Eastern equine encephalitis vaccine<br />

effectiveness when antiserum is added, 329<br />

ECHO virases, 241, 246<br />

isolation from suspected polio cases, 571<br />

occurrence, 421, 537<br />

ECHO 1<br />

antiserum added to fecal suspensions before<br />

poliovirus isolation, 203<br />

ECHO 1-14<br />

identified, 271<br />

ECHO 2, 14<br />

in 7 unvaccinated infants, 273<br />

ECHO 7, 8, 12, 14<br />

isolated, Costa Rica, 575<br />

ECHO 7, 14, 19<br />

restricted to Franklin, Louisiana, 151<br />

ECHO 8, 257<br />

effect on spread of vaccine, 263<br />

ECHO 10<br />

similar to SA-III, 86<br />

ECHO 12<br />

interference, 181<br />

ECHO 14, 19<br />

restricted to Morgan City, Louisiana, 151<br />

ECMO viruses, see Simian viruses<br />

Ecological behlavior, described, 110, 603<br />

Economic conditions, see Socio-economic conditions<br />

Effectiveness<br />

analysis depends on triple negatives, 373, 444<br />

and change in markers, 7<br />

calculation on basis of all cases, 481<br />

Cincinnati, Ohio, 591<br />

controls selection, important in evaluating, 506<br />

Effectiveness-continued<br />

criterion, 4, 371, 568, 579, 602<br />

difference between number of expected and observed<br />

cases, 401<br />

four Soviet republics, 497<br />

high degree, 577<br />

immunological and epidemiological, 482-501<br />

Leopoldville, Congo, 466-473<br />

long-range, determination, 445<br />

Netherlands, 143<br />

radical breakdowns in seasonal rise in polio, 493<br />

related to interval between doses, 116<br />

trivalent vaccine in young children, 113-120<br />

Eiger, Marvin S., paper, 315-321<br />

Eklund, C. M., 459, 462<br />

Electrostal, USSR, 242<br />

Elution marker<br />

differential adsorption on cellulose columns, 13<br />

method detailed, 42, 43<br />

Embil, Juan, paper 330-340, 365-370; 330<br />

Embu district, Kenya, 479<br />

EMC virus, possible contaminant, 474<br />

Encephalitis<br />

in 9-year-old vaccinee, 593<br />

incidence through trial period, 454<br />

End point technique<br />

not sensitive enough, 237<br />

Endanmoeba coli, Cuban children infested, 368<br />

Endemic areas, Japan<br />

infants immunized with Salk, 191<br />

Enders, J. F., 5<br />

Endocrine factor<br />

susceptibility after birth enhanced, 300<br />

England<br />

maternal antibody half-life study, 294<br />

Type 3 specimens, 124<br />

Enjoji, Dr.- (of Fukuoka University), 193<br />

Enteroviruses<br />

and response to vaccination, 122, 179, 271, 274<br />

clinical manifestations, 157<br />

dissemination of, 411<br />

86 episodes, 150<br />

from sewage samples, a study, 439<br />

identified in stools, 273, 368, 439<br />

incidence compared with polioviruses, 380<br />

interference, 8, 378, 394, 429, 575, 602<br />

isolation, 400, 570, 591<br />

Louisiana study, tabulated, 152, 153<br />

prevalence among children, 182, 243<br />

search in monkey kidney and human cell line, 123<br />

Environment<br />

relation to results, 121<br />

subtropical and polio, 184<br />

Epidemics<br />

Aland archipelago, 1953, 536<br />

and opponents of live virus vaccine, 8<br />

Costa Rica, 1954, 561, 569, 575<br />

Des Moines<br />

specific attack rates by dose and socio-economic<br />

class, 375<br />

evolution, Nicaragua, 1959-60, 559<br />

Hungary, 1959, 518<br />

in lower economic groups, 158

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